Biologically Active Substances from the GenusArtemisia

Abstract

Artemisia species, widespread in nature, are frequently utilized for the treatment of diseases such as malaria, hepatitis, cancer, inflammation, and infections by fungi, bacteria, and viruses. Furthermore, some Artemisia constituents were found to be potential insecticides and allelopathic chemicals. This genus is receiving growing attention presumably due to: (i) the diversified biology and chemistry of the constituents, (ii) the frequent application in traditional medical practice, and (iii) the rich source of the plant material. This review summarizes mainly the biological results obtained in the past decade. The significance and trends in this field are briefly discussed.

Anti-cancer Properties of a Sesquiterpene Lactone-bearing Fraction from Artemisia khorassanica

“…The Artemisia genus has been used in folk medicine for many years; numerous reports have indicated a vast range of biological effects associated with different Artemisia species (Abad Martinez et al, 2012;Choi et al, 2013). Among the various chemical agents found in these plants, sesquiterpene lactones have been proven to impart anticancer effects (Tan et al, 1998;Firestone et al, 2009;Firestone 2009;Lu 2009;Zhai 2010;Feng 2013).…”

Adaptation of Farm Field Transplanting and Growth Habitat of Artemisia capillaris in Korea

“…사철쑥은 더위지기 (Artemisia gmelini Weber)와 함께 한방 에서 인진 종류라 하여 해열, 진통, 혈압강하, 담즙분비 촉진 등에 이용함은 물론 독성이 거의 없으므로 식품공정상 주원료 로 사용이 가능한 식물자원이다 (Tan et al, 1998) 때문에 관 련 연구는 사철쑥 주요 약리성분의 scoparone (Yamahara et al, 1989;Huang et al, 1991)과 capillarisin (Komiya et al, 1975) 및 그 효능 (Kiso et al, 1984;Lee et al, 2004)에 집중되었다. 이밖에도 항염증, 이뇨제, 항암, 간보호 및 항산화 작용 (Ikenaga et al, 1994;Hwang et al, 1999;Seo et al, 2003;Kim et al, 2005), 타감물질 효과 (Kil, 1999) 등이 보고되었다.…”

Experimental immunology The effect of multi-component herbal remedy PERVIVO on cellular immunity and tumor angiogenesis in mice

“…Extracts from wormwood contain a variety of phenolic and flavonoid compounds and exert antibacterial, antiplasmodial, antitrypanosomal and antihelminthic activity [1][2][3][4][5]. Recently, suppression of tumor-necrosis factor alpha by A. absinthium extracts in vitro was reported [6] and clinically tested in patients with Crohn's disease and IgA nephropathy [7].…”

“…It should be remembered, however, that the intake of Absinthii herba preparations might influence the effect of medicinal products acting via GABA receptor (e.g. barbiturates, benzodiazepines) [1,11].…”