Biological properties of polyurethane: Issues and potential for application in vascular medicine

Non-isocyanate polyurethane-co-polyglycolic acid electrospun nanofiber membrane wound dressing with high biocompatibility, hemostasis, and prevention of chronic wound formation

“…When applied to a wound, electrospun nanofiber membranes, as having numerous pore structures, can quickly absorb blood and promote platelet aggregation for rapid hemostasis [ 15 ]. At the same time, studies have demonstrated that the surface polarity of polyurethane materials can cause blood coagulation by promoting the deposition of fibrin and platelets [ 85 , 86 ]. The current study also shows that the structure of polyurethane's microphase separation has an adsorption effect on protein, which increases as the degree of microphase separation decreases [ 87 ].…”