Biological Importance and Pharmacological Activities of Meranzin and Meranzin Hydrate Against Human Disorders

Abstract

Background: Herbal plant based products and their derived phytochemicals have been used in the complementary and alternative system of medicine for the treatment of human disorders. Vegetables, fruits, seeds, nuts, coffee, tea, and wine contain significant amounts of coumarin class phytochemicals. Coumarin is found to be present in cassia leaf oil, cinnamon bark oil, lavender oil and in microorganism derived drugs. Methods: Scientific databases such as Google, Google Scholar, Science Direct, Scopus, and PubMed have been searched to collect the scientific information of meranzin and meranzin hydrate in the present work in order to know the medicinal importance and pharmacological activities in the medicine. Pharmacological activity data of meranzin and meranzin hydrates has been thoroughly studied from these scientific databases and analyzed in the present work to know their biological potential against human disorders. Analytical data of meranzin and meranzin hydrates have been also collected and analyzed in the present work to know the importance of analytical techniques for the standardization of plant material. Results: Scientific data analysis revealed the biological potential of meranzin and meranzin hydrates against human health complications. Meranzin were found to be present in the Fructus aurantii, Triphasia trifolia, Cnidium monnieri and Murraya exotica. Scientific data analysis revealed the biological potential of meranzin and meranzin hydrates in the medicine due to its anti-depressant, anti-fibrotic, anti-proliferative, and anti-atherosclerosis, anti-bacterial activities. Further scientific data analysis revealed the biological effectiveness of meranzin and meranzin hydrates on neuroinflammation, intestinal motility and various forms of enzymes. Pharmacokinetic parameters for meranzin and meranzin hydrates have been also investigated in the present work. Chromatography techniques used for the analysis have been also summarized and discussed in the present work to know the importance of isolation, separation, and quantification of meranzin and meranzin hydrates. Conclusion: Present study will be supportive to the scientist for the development of effective medicine from meranzin and meranzin hydrates against various form of human health complications.