Biological Activities of Mesembryanthemum crystallinum (Ice plant) Extract

이상률,; 최현덕,; 유선녕,; 김상헌,; 박슬기,; 안순철,

doi:10.5352/jls.2015.25.6.638

Cited by 15 publications

(10 citation statements)

References 29 publications

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“…This ability to overcome difficult environment conditions can be attributed to antioxidant activity, derived mainly from phenolic compounds [119][120][121]. Halophytes are thus of interest both for therapeutic cosmetics and food [122,123]. M. crystallinum and M. nodiflorum were used in Tunisian folkloric medical treatments against ocular infection [124], and the leaf extracts are traditionally used as preservatives, as a remedy against throat and mouth infections [125], in soap-making [126] ( Figure 5), and to treat several cancers [127,128].…”

Section: Human Healthmentioning

confidence: 99%

“…M. crystallinum and M. nodiflorum were used in Tunisian folkloric medical treatments against ocular infection [124], and the leaf extracts are traditionally used as preservatives, as a remedy against throat and mouth infections [125], in soap-making [126] ( Figure 5), and to treat several cancers [127,128]. The juice from the leaves can be used to treat several fungal and bacterial diseases, sinusitis, diarrhea, infantile eczema, tuberculosis, and other disorders such as diabetes or obesity [122,126,129]. It is also used to treat inflammation of the respiratory or urinary systems, water retention, and painful urination, and for soothing lung inflammation [130] and spider and tick bites [131].…”

Section: Human Healthmentioning

confidence: 99%

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Halophyte Common Ice Plants: A Future Solution to Arable Land Salinization

Loconsole

Murillo-Amador²,

Cristiano

et al. 2019

Sustainability

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The problems associated with the salinization of soils and water bodies and the increasing competition for scarce freshwater resources are increasing. Current attempts to adapt to these conditions through sustainable agriculture involves searching for new highly salt-tolerant crops, and wild species that have potential as saline crops are particularly suitable. The common ice plant (Mesembryanthemum crystallinum L.) is an edible halophyte member of the Aizoaceae family, which switches from C3 photosynthesis to crassulacean acid metabolism (CAM) when exposed to salinity or water stress. The aim of this review was to examine the potential of using the ice plant in both the wild and as a crop, and to describe its ecology and morphology, environmental and agronomic requirements, and physiology. The antioxidant properties and mineral composition of the ice plant are also beneficial to human health and have been extensively examined.

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Section: Human Healthmentioning

confidence: 99%

Section: Human Healthmentioning

confidence: 99%

Halophyte Common Ice Plants: A Future Solution to Arable Land Salinization

Loconsole

Murillo-Amador²,

Cristiano

et al. 2019

Sustainability

View full text Add to dashboard Cite

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“…Mesembryanthemus species are known as halophytic models due to the methods of salt tolerance utilized by these plants [9]. The Mesembryanthemum genus has three edible species of interest: M. edule, M. crystallinum and M. nodiflorum [10,11].…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Properties of a Supercritical Fluid Extract of the Halophyte Mesembryanthemum nodiflorum L. from Sicilian Coasts: Nutraceutical and Cosmeceutical Applications

et al. 2020

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The aim of this paper was to obtain different extracts from the aerial parts of Mesembryanthemum nodiflorum, comparing traditional extraction (using solvents with increasing polarity such as hexane, ethanol 80%, acetone 70% and water) with an eco-friendly technique (supercritical fluid extraction (SFE)); to evaluate which extract showed a higher amount of antioxidants and then evaluate the bioactive properties in vitro, in human fibroblast (HS68). From the six extracts obtained it was observed that the solvent with the highest extraction efficiency was water, but the extracts in ethanol, N-hexane and SFE are those that showed the highest antioxidant activity (polyphenols, 1,1-Diphenyl-2-picrylhydrazyl (DPPH) and reducing power). On the basis of these results, the SFE extract was chosen to evaluate the antioxidant and anti-aging activity in vitro, by assessing cell vitality and molecular markers (MTT and immunoblotting assays). The results showed that the SFE extract exerted antioxidant activity in vitro, protecting cells from mortality induced by oxidative stress; this protection was also confirmed at the molecular level, by the levels of the protein integrin -1, that is able to prevent the negative effects of a stress situation, such as oxidative stress, that could promote aging and related diseases. This extract, obtained with an eco-friendly technique, given its beneficial properties, could be used for application in nutraceuticals and cosmeceuticals.

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“…Ice plant의 활성으로는 항산화 성분 함량 [8,9], radical 소거 활성 [8,[10][11][12], α-glucosidase 저해 활성 [8,10,11], α-amylase 저해 활성 [8], nitric oxide 저해 활성 [11], angiotensin converting enzyme 저해 활성 [13], 항균 효과 [12], 고혈당 및 기억력 개선 활성 [14] 등이 보고된 바 있다.…”

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“…Ice plant의 블러더 세포는 D-pinitol, ononitol, myo-inositol 등의 polyol류를 함유하여 항산화 활성 [1,8]을 나타낸다고 보고된 바 있으며, 이중 D-pinitol의 경우 혈당 감소 [11,15]…”

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Antioxidant and growth inhibitory activities ofMesembryanthemum crystallinumL. in HCT116 human colon cancer cells

서

Song

2019

J Nutr Health

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Purpose: This study examined the antioxidant and cancer cell growth inhibitory activities of an ethanol extract and different solvent fractions of Mesembryanthemum crystallinum L. (ice plant). Methods: The ice plant was freeze-dried, extracted with 99.9% ethanol, and then fractionated with hexane, ethyl acetate, butanol, and water. The total polyphenol content (TPC), total carotenoid content (TCC), 2,2-diphenyl-1-picrylhydrazyl radical-scavenging activity (RSA), and ferric reducing antioxidant power (FRAP) were measured. Assays using 2',7'-dichlorofluorescin-diacetate and 3-(4,5-dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide were performed to measure the intracellular reactive oxygen species (ROS) and cell growth, respectively. Annexin V/propidium iodide staining and cell cycle analysis were performed for the detection of apoptosis and cell cycle arrest. Results: TPC, TCC, RSA, and FRAP of the ethanol extract (EE) were 3.7 mg gallic acid equivalent/g, 13.2 μg/g, 21.0% (at a concentration of 5 mg/mL), and 21.0% (at a concentration of 5 mg/mL), respectively. Among the different solvent fractions, the butanol fraction (BF) showed the highest TPC (5.4 mg gallic acid equivalent/g), TCC (86.6 μg/g), RSA (34.9% at 5 mg/mL), and FRAP (80.8% at 5 mg/mL). Treatment of HCT116 human colon cancer cells with EE and BF at concentrations of 250 and 500 μg/mL reduced the levels of intracellular ROS. Concomitantly, EE and BF resulted in the dose-dependent inhibition of cell growth (at the concentrations of 125, 250, and 500 μg/mL for 24~48 h) and the induction of apoptosis (at the concentrations of 250 and 500 μg/mL for 48 h) in HCT116 cells. An increased G2/M cell population was also found in the BF-treated cells. Conclusion: These results suggest that ice plant possesses antioxidant and growth inhibitory activities in colon cancer cells.

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Biological Activities of Mesembryanthemum crystallinum (Ice plant) Extract

Cited by 15 publications

References 29 publications

Halophyte Common Ice Plants: A Future Solution to Arable Land Salinization

Halophyte Common Ice Plants: A Future Solution to Arable Land Salinization

Antioxidant Properties of a Supercritical Fluid Extract of the Halophyte Mesembryanthemum nodiflorum L. from Sicilian Coasts: Nutraceutical and Cosmeceutical Applications

Antioxidant and growth inhibitory activities ofMesembryanthemum crystallinumL. in HCT116 human colon cancer cells

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