Biological Activities, DFT and Molecular Docking Studies of Novel Schiff Bases Derived from Sulfamethoxypyridazine
Muhammad Wajid,
Muhammad Uzair,
Gulzar Muhammad
et al.
Abstract:The present study reported the synthesis and biological activities of sulfamethoxypyridazine (SMPR) Schiff bases (SBs) with different aromatic aldehydes. The antimicrobial potential of SBs against various pathogenic strains (S. epidermidis, E. coli, S. agalactiae, S. aureus, S. typhi, K. pneumoniae, C. albicans, and C. tropicalis) was explored by disc diffusion method. The antidiabetic potential was monitored by inhibition of α‐amylase, α‐glucosidase, and anti‐inflammatory activity was studied by protein denat… Show more
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