2010
DOI: 10.1590/s1413-81232010000600022
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Biologia do envelhecimento: teorias, mecanismos e perspectivas

Abstract: The article reviews the major biological theories of aging, and discusses the most relevant mechanisms to explain the aging process. It begins with the evolutionary theories, explores the molecular-cellular mechanisms, and presents the perspective of the systemic theories. The complex etiology of aging is a challenge to the researchers. The knowledge on that phenomenon develops towards an integrative approach.

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Cited by 37 publications
(29 citation statements)
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“…The loss or decline of balance results in a major public health problem: falls. The imbalance results from interactions of the musculoskeletal, visual, and sensorimotor systems and related functional tasks that undergo changes with senescence, such as sarcopenia, proprioceptive alterations, joint stiffness, postural alignment, latency and temporal incoordination of muscle activation [1][2][3][4].…”
Section: Introductionmentioning
confidence: 99%
“…The loss or decline of balance results in a major public health problem: falls. The imbalance results from interactions of the musculoskeletal, visual, and sensorimotor systems and related functional tasks that undergo changes with senescence, such as sarcopenia, proprioceptive alterations, joint stiffness, postural alignment, latency and temporal incoordination of muscle activation [1][2][3][4].…”
Section: Introductionmentioning
confidence: 99%
“…2 From a biological perspective, aging is marked by progressive alterations in cells, tissues, and organs, impacting functional capacity and increasing susceptibility to chronic diseases. 3 These factors contribute to increased risk of loss of skin integrity, and consequently, to the emergence of ulcers.…”
Section: Introductionmentioning
confidence: 99%
“…El envejecimiento es un proceso biológico y natural al que nos enfrentamos desde que nacemos y que varía de acuerdo con la herencia y predisposición genéticas, las características intrínsecas de cada individuo y la acción de múltiples factores externos (Teixeira y Guariento, 2010 (Franco, 2009).…”
Section: Desarrollounclassified