Bioinspired Polyoxomolybdate Nanoclusters Peroxidase‐Mimicking Nanozyme for Dual‐Mode Detection of Methotrexate in Real Samples
Sina Azarian,
Gholamreza Dehghan,
Mojtaba Amini
Abstract:Methotrexate (MTX) is a chemotherapy agent and immune system suppressant that is widely used to treat a variety of malignant and nonmalignant diseases. Due to some drawbacks of the existing methods for the determination of MTX in aquatic and real samples, we prepared a new, simple, and selective dual‐mode fluorometric and electrochemical approach based on peroxidase‐mimic [Mo36] polyoxomolybdate nanoclusters (POMo) for sensing MTX. A turn‐on–off fluorometric approach for the detection of MTX was developed, whi… Show more
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