Bioinspired Natural Magnolol-Based Adhesive with Strong Adhesion and Antibacterial Properties for Application in Wet and Dry Environments

Abstract

The development of environmentally friendly, green, and nontoxic adhesives with excellent dry and wet adhesion properties is of great attraction. In nature, barnacles and mussels exhibit strong adhesion by secreting a hydroxyl-rich dopa. Inspired by their adhesion mechanism, a simple biobased MAG-PETMP (MP) adhesive was prepared from magnolol (MAG) and pentaerythritol tetra (3-mercaptopropionate) (PETMP) by a thiol–ene click chemistry reaction. MP as an adhesive exhibits high bond strength with other substrates due to hydrogen bonds formed by the abundant hydroxyl groups at the interface and shows an inherent thermosetting network structure. Since MP has a thermosetting network, it exhibits excellent thermal stability, solvent resistance, and high mechanical strength, which make the adhesive stable in a humid environment. The cross-linking degree of MP can be easily controlled by adjusting the molar ratio of MAG and PETMP. Among the synthesized samples, the elongation at break of the MP 1 formulation is 174.27%, which makes it promising for use as a flexible adhesive. Moreover, the inherent antibacterial properties of MAG enable MP to exhibit antimicrobial properties and antibacterial adhesion to some extent. This work provides a simple biomimetic strategy that could enable the application of MAG for adhesives.

Synthesis and Fabrication of Betulin-Derived Polysulfide and Polysulfoxide Electrospun Fibers for Fruit Preservation

“…Polymer materials derived from renewable resources with antimicrobial properties, utilizing photoinduced thiol–ene reactions, not only exhibit inherent biological activity of corresponding monomers but also demonstrate the processability and formability of polymers. , We have previously confirmed that modified derivatives of betulin can be used as antibacterial comonomers in dental resins. , The colonies on the culture plates treated with methacrylated betulin appeared less dense compared with those treated with parent betulin, indicating an enhanced inhibition of bacterial growth attributed to increased hydrophobicity. These promising results support the utilization of methacrylated betulin in the development of dental resins with satisfactory antibacterial properties.…”

“…The advancement of polymeric materials with varying complexity and diversity has enabled the production of copolymers with accurate molecular weights, architectures, and functional groups, all of which have a range of structures, properties, and applications. − Over the past decade, click chemistry has emerged as a promising strategy for engineering the architecture and functionality of materials, allowing for the production of functional synthetic polymers and modified polymeric materials. , Polysulfides are high-performance polymeric materials containing sulfur components and can be prepared directly from thiol–ene polymerization, playing a crucial role in the development of specialty applications. − This reaction is generally characterized by high yields, low catalyst concentrations, fast reaction rates, and the ability to be conducted in bulk or in eco-friendly solvents at various concentrations . Rational monomer design facilitates the construction of functionalized polymers with diverse compositions, especially by utilizing renewable sources from the agricultural and food kingdoms, such as carbohydrates, , phenolic acids, , isosorbide, , and biocompounds. − This approach provides an environmentally friendly alternative to petroleum-based polymers for the fabrication of sustainable polymeric materials. Hydrogen peroxide can be produced endogenously by cells in living organisms, and it serves as an oxidant in biological systems .…”

Role of magnolol embedded fully bio-based benzoxazines for hydrophobic, anti-microbial and anti-corrosion applications

“…25,26 Magnolol has also been used as an antioxidant, antiviral, and antibacterial agent. 27 In the field of polymer chemistry, magnolol has been used in the preparation of adhesives 28 and epoxy resin, 29,30 for intrinsic flame-retardant applications due to its high heat-resistant behaviour. Limited literature pertaining to magnolol-based benzoxazines has been published to date.…”