Bioinspired Materials for Wearable Diagnostics and Biosensors

Bardhan, Neelkanth M.; Radišić, Milica; Nurunnabi, Md

doi:10.1021/acsbiomaterials.3c00348

Cited by 4 publications

(2 citation statements)

References 36 publications

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“…Next-generation diagnostic biosensor prototypes could, however, be further improved to enhance their potential adoption by advances in biomimetic and conformable materials, low-energy power harvesting/generation methods, wireless communication approaches, and signal transducer and detector sensitivity increases [ 74 ]. Advances in AI-based data analysis applications, bioinformatics, cloud-based data storage, the Internet of Things, and cellular communication in the biomedical sector could also enhance their utility and clinical adoption [ 75 ].…”

Section: Novel Technologies For Eid Monitoring and Screeningmentioning

confidence: 99%

Climate change, its impact on emerging infectious diseases and new technologies to combat the challenge

Liao,

Lyon,

Ying

et al. 2024

Emerging Microbes & Infections

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Improved sanitation, increased access to health care, and advances in preventive and clinical medicine have reduced the mortality and morbidity rates of several infectious diseases. However, recent outbreaks of several emerging infectious diseases (EIDs) have caused substantial mortality and morbidity, and the frequency of these outbreaks is likely to increase due to pathogen, environmental, and population effects driven by climate change. Extreme or persistent changes in temperature, precipitation, humidity, and air pollution associated with climate change can, for example, expand the size of EID reservoirs, increase host–pathogen and cross-species host contacts to promote transmission or spillover events, and degrade the overall health of susceptible host populations leading to new EID outbreaks. It is therefore vital to establish global strategies to track and model potential responses of candidate EIDs to project their future behaviour and guide research efforts on early detection and diagnosis technologies and vaccine development efforts for these targets. Multi-disciplinary collaborations are demanding to develop effective inter-continental surveillance and modelling platforms that employ artificial intelligence to mitigate climate change effects on EID outbreaks. In this review, we discuss how climate change has increased the risk of EIDs and describe novel approaches to improve surveillance of emerging pathogens that pose the risk for EID outbreaks, new and existing measures that could be used to contain or reduce the risk of future EID outbreaks, and new methods to improve EID tracking during further outbreaks to limit disease transmission.

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Section: Novel Technologies For Eid Monitoring and Screeningmentioning

confidence: 99%

Climate change, its impact on emerging infectious diseases and new technologies to combat the challenge

Liao,

Lyon,

Ying

et al. 2024

Emerging Microbes & Infections

View full text Add to dashboard Cite

show abstract

“…Diabetes is one of the major public health challenges nowadays, threatening more than 537 million people worldwide . Blood-glucose monitoring and regulating technologies have received sustained attention from the academia and industry. − Recently, scientists tried to design noninvasive/microinvasive systems (e.g. smart contact lens, microneedles) for long-term blood-glucose monitoring.…”

Section: Introductionmentioning

confidence: 99%

Electrostatic-Interaction-Aided Microneedle Patch for Enhanced Glucose-Responsive Insulin Delivery and Three-Meal-Per-Day Blood-Glucose Regulation

Shen,

Yu,

Wang

et al. 2024

ACS Appl. Mater. Interfaces

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The phenylborate-ester-cross-linked hydrogel microneedle patch (MNP) was promising in the diabetic field for the glucose-responsive insulindelivering property and simple fabrication process. However, the unfit design of the charging microneedle network limited the improvement of blood-glucose regulating performances. In this work, insulin-loaded phenylborate-ester-crosslinked MNPs, with the polyzwitterion property, were constructed based on the modified ε-polylysine and poly(vinyl alcohol). The relationship between the charging nature of the MNP network and insulin release was verified by regulating the content of postprotonated positively charged amino groups. The elaborately designed MNP possessed improved glucose-responsive insulindelivering performance. The in vivo study revealed the satisfactory results on blood-glucose regulation by the optimized MNP under the mimic three-mealper-day mode. Moreover, the insulin bioactivity in the MNP could be maintained for 2 weeks under 25 °C. In summary, this work developed an effective strategy to improve the glucose-responsive phenylborateester-cross-linked MNP and enhance its potential for clinical transformation.

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Innovative use of optical sensors for real-time imaging and diagnosis using enhanced verge denoising and LSTM for sports medicine

Zhang,

xie,

Gao

2024

Opt Quant Electron

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Bioinspired Materials for Wearable Diagnostics and Biosensors

Cited by 4 publications

References 36 publications

Climate change, its impact on emerging infectious diseases and new technologies to combat the challenge

Climate change, its impact on emerging infectious diseases and new technologies to combat the challenge

Electrostatic-Interaction-Aided Microneedle Patch for Enhanced Glucose-Responsive Insulin Delivery and Three-Meal-Per-Day Blood-Glucose Regulation

Innovative use of optical sensors for real-time imaging and diagnosis using enhanced verge denoising and LSTM for sports medicine

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