Bioinspired artificial nanochannels: construction and application

Abstract

Biological channels facilitate the transport of ions and molecules across cell membranes. They can response to various external stimuli such as light, ions, changes of pH, temperature and so on,...

Investigating Ion Transport through Artificial Transmembrane Channels Containing Introverted Groups

“…[ 1 ] Because of the important function of the natural ion channels, chemists have great interests in the construction of artificial channels to mimic the functions of channel proteins, which not only is fundamentally important for exploring the ion transport and gating mechanisms, but also would find applications in the developing molecular devices, separation materials, and therapeutic reagents. [ 2 ] In the past decades, a large number of artificial channels have been built in the lipid bilayers and cell membranes through precisely structural designing, which could be divided into two categories: self‐assembled supramolecular and preorganized unimolecular systems. The self‐assembled channels are composed of two or more molecules that are assembled driven by intermolecular non‐covalent interactions.…”

A DNA-Schiff base functional nanopore sensing platform for the highly sensitive detection of Al3+and Zn2+ions

“…[4][5][6] The artificial solidstate nanopores include polyethylene terephthalate films, 7 anodized alumina oxide membranes, 8 carbon nanotubes, 9 and glass nanopipettes (GNs). 10 The GN has attracted increasing attention owing to the merits of strong plasticity, low cost, and high resolution of analysis and detection. [11][12][13] Recently, the highly sensitive and selective detection of K + , 14 Ag + , 15 Hg 2+ , 16 Zn 2+ , 17 and other ions has been realized by combining DNA and protein molecules, gold nanoparticles, and metal-organic frameworks (MOFs) with artificial nanopores.…”

Tailoring Enantiomeric Chiral Channels in Metal‐Peptide Networks: A Novel Foldamer‐Based Approach for Host‐Guest Interactions

“…Organic porous materials with well‐defined chiral channels have attracted significant attention in recent years due to their potential applications across various fields, such as asymmetric catalysis, [ 1 ] chiral separation, [ 2 ] enantioselective chemical sensing, [ 3 ] and chiroptical materials. [ 4 ] While a variety of porous materials, including open crystalline frameworks, [ 5 ] molecular cages, [ 6 ] and polymers, [ 7 ] have been explored as platforms for fabricating chiral channels, metal‐peptide networks (MPNs) [ 8 ] hold the most promise for developing chiral porous structures. MPNs consist of peptide scaffolds interconnected by metal ions (or metal clusters) and offer countless combinations of metals and peptides with intrinsic chirality.…”