Bioinorganic Interface: Mechanistic Studies of Protein-Directed Nanomaterial Synthesis

Roth, Kristina L.; Geng, Xi; Grove, Tijana Ž.

doi:10.1021/acs.jpcc.6b02569

Cited by 11 publications

(9 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These molecules are interesting as surface coatings, due to their biocompatibility, and they may possess different metal binding sites. Reports on protein‐directed anisotropic nanoparticle synthesis[10b,11] validate the potential usefulness of such synthesis routes, but a deeper understanding of reaction mechanisms, in particular concerning shape‐control, is still needed . Some review articles describe the role of proteins, peptides, and other biomolecules in the synthesis of inorganic nanoparticles, but without giving emphasis to shape control.…”

Section: Introductionmentioning

confidence: 99%

Protein‐Induced Shape Control of Noble Metal Nanoparticles

Chakraborty

Parak

2019

Adv Materials Inter

View full text Add to dashboard Cite

Shape control of nanoparticles results in tuned optical properties which are indeed beneficial for different bio‐based applications. Shape controls in major cases, governed by toxic surfactants or harsh solvent conditions. To avoid the toxicity of surfactants used as shape controlling agent, different bio‐inspired synthesis of noble metal nanoparticles are developed. Proteins play a significant role here to create anisotropic nanoparticles without the use of any toxic surfactants. Various shape and size of nanoparticles are developed so far based on proteins. This progress report summarizes such protein‐induced shape controls of different noble metal nanoparticles and explain the recent understandings of this method from mechanistic point of view. The report also explains the new opportunities in this direction in near future.

show abstract

Section: Introductionmentioning

confidence: 99%

Protein‐Induced Shape Control of Noble Metal Nanoparticles

Chakraborty

Parak

2019

Adv Materials Inter

View full text Add to dashboard Cite

show abstract

“…The 1 H- 15 N HSQC NMR and fluorescence quenching studies have been carried out in our lab to interrogate the interaction between the CTPR protein and noble metals. 53 Binding of Au(III) to CTPR is driven by the overall electrostatics, with tryptophan, tyrosine and asparagine side chains coordinating the metal ion. Guided by that knowledge, we hypothesized that CTPR will similarly interact with silver ions and thus exert control over the kinetics, crystalline structure and preferential growth of silver NPs.…”

Section: Introductionmentioning

confidence: 99%

Protein-aided formation of triangular silver nanoprisms with enhanced SERS performance

et al. 2016

Self Cite

View full text Add to dashboard Cite

show abstract

“…AuNPs are biocompatible in nature, and show strong light scattering, optoacoustic signaling, and high absorption rate with less bone or tissue interference which leads to their applications in diverse fields including biomedical (imaging, diagnostics, photothermal therapy, and drug delivery), electronics, catalysis, sensors . The biomedical applications account for more than half global market share.…”

Section: Gold Nanoparticles and Their Antibacterial Applicationsmentioning

confidence: 99%

Advances in the Experimental and Theoretical Understandings of Antibiotic Conjugated Gold Nanoparticles for Antibacterial Applications

2019

View full text Add to dashboard Cite

The worldwide bacterial resistance to a wide range of antibiotics originates a global health concern and calls for the development of new antibacterial agents. Over the recent years, nanomaterials-based agents have been proven to be useful for the effective antibacterial applications. Notably, the gold nanoparticles (AuNPs) draw particular attention due to their biological inertness and easy surface functionalization. It is now established that the antibiotic functionalization on the AuNPs surfaces increases the antibacterial efficacy even towards the antibiotic-resistant bacterial cells. Moreover, the antibacterial efficacy can be further enhanced by photothermal therapy using antibiotic conjugated AuNPs. In this review article, we have reviewed the advances in the development of the synthesis methods of antibiotic conjugated AuNPs and gold nanoclusters, and their antibacterial efficacy. We have also discussed the developments in the theoretical understandings behind the interaction of antibiotic molecules with gold surface and its relation to the antibacterial activity. We believe that few parameters including the selection of antibiotic molecules, the method of its attachment to AuNPs, the purification of antibiotic conjugated AuNPs, and the quantification of conjugated antibiotic are crucial and needs to be properly addressed. Moreover, there are many other future directions discussed, for using antibiotic conjugated AuNPs more effectively for antibacterial therapy.[a] Dr.

show abstract

Bioinorganic Interface: Mechanistic Studies of Protein-Directed Nanomaterial Synthesis

Cited by 11 publications

References 65 publications

Protein‐Induced Shape Control of Noble Metal Nanoparticles

Protein‐Induced Shape Control of Noble Metal Nanoparticles

Protein-aided formation of triangular silver nanoprisms with enhanced SERS performance

Advances in the Experimental and Theoretical Understandings of Antibiotic Conjugated Gold Nanoparticles for Antibacterial Applications

Contact Info

Product

Resources

About