Bioinformatics Analysis of Immune Cell Infiltration Patterns and Potential Diagnostic Markers in Atherosclerosis
Haigang Ji,
Ling Yuan,
Wenbo Jiang
et al.
Abstract:Background
This study aimed to investigate efficient diagnostic markers and molecular mechanisms of atherosclerosis and to analyze the role of immune infiltration through bioinformatics analysis.
Results
Expression profile datasets (GSE28829 and GSE43292) of patients with atherosclerosis and healthy controls were downloaded from the GEO database. Glutamine (GLN) metabolism-associated genes were obtained from the Molecular Signatures Database (MSigDB). The limma package in R was used to identify differentiall… Show more
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