Bioimpedance analysis highlights changes in body composition at the early stages of impairment of kidney transplant function

Coroas, Andreia S.P.S.; Oliveira, José Arimátes de; Sampaio, Susana; Borges, C.; Tavares, Isabel; Pestana, Manuel; Almeida, Maria Clotilde

doi:10.1053/j.jrn.2004.04.005

Cited by 6 publications

(2 citation statements)

References 16 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As expected, our data certifies that a good kidney graft clearly outperforms dialysis as far as body composition correction concerns. We believe that BIA may help in nutritional advice of sodium and fluid intake, and in monitoring the impact of drugs that may interfere with this equilibrium among kidney Tx patients, mirroring our findings among psoriatic patients with normal renal function treated by cyclosporine [32]. …”

Section: Discussionsupporting

confidence: 65%

Body Composition Assessed by Impedance Changes Very Early with Declining Renal Graft Function

Coroas¹,

Oliveira²,

Sampaio³

et al. 2006

Nephron Physiol

View full text Add to dashboard Cite

Background: Kidney transplant (Tx) restores renal filtration, although it does not achieve the function of two native kidneys, and with time it may variably involute back to chronic renal failure. We hypothesized that bioelectrical impedance analysis (BIA) might highlight differences for body compartments among Tx with different filtration rates, and we compared them with healthy controls. Methods: 38 Tx patients (25 males, 13 females) were studied at 75.9 ± 37.8 months postsurgery and divided into three groups: good creatinine clearance (CrCl, ml/min/1.73 m²; > 65.0), borderline (35.0 < CrCl < 60.0) and bad (CrCl < 35.0). BIA was assessed three times in a year. Total body water, extracellular water (ECW), intracellular water (ICW), Na:K exchange rate (Nae:Ke) and phase angle were studied. Healthy (n = 11) and hemodialysis (n = 11) groups were also studied. Results: BIA showed no differences between healthy controls and good Tx while both borderline and bad Tx presented a significantly higher ECW and lower ICW than either good Tx or normal controls. Only good CrCl was different from predialysis. Conclusions: A good kidney graft manages to restore and maintain normal body composition, even with potential disturbances brought about by steroids and cyclosporine. With mild renal dysfunction a change in body compartments was observed, moving towards the composition of that with chronic renal failure patients.

show abstract

Section: Discussionsupporting

confidence: 65%

Body Composition Assessed by Impedance Changes Very Early with Declining Renal Graft Function

Coroas¹,

Oliveira²,

Sampaio³

et al. 2006

Nephron Physiol

View full text Add to dashboard Cite

show abstract

“…(compatible with stage 3A chronic kidney disease), and previous studies conducted with RTR observed significantly higher extracellular water with decreasing values of eGFR. 61,62 This is a pioneer study showing in a RTR population an inverse correlation between PhA and central body adiposity. High body adiposity is widely associated with inflammation and insulin resistance.…”

Section: Considering This Difference Between Groups and The Differencmentioning

confidence: 97%

High abdominal adiposity and low phase angle in overweight renal transplant recipients

Ferreira

Silva

Costa

et al. 2019

Clinical Transplantation

View full text Add to dashboard Cite

Obesity is associated with increased risk of cardiovascular disease (CVD). Body mass index (BMI) is the most used parameter for obesity screening. However, the evaluation of CVD risk in overweight individuals should include the assessment of body fat distribution and body composition. Renal transplant recipients (RTR) have a high CVD risk and frequently present weight gain and loss of lean mass. The aim of this study was to evaluate body fat distribution and body composition in overweight RTR. This cross‐sectional study was conducted with 86 RTR and 86 hypertensive individuals (comparison group, CG) presenting BMI 25‐35 Kg/m2 and 45‐70 years. Anthropometric evaluation included BMI, waist circumference, waist‐to‐height ratio, and a body shape index. Body composition was evaluated with bioelectrical impedance analysis (BIA). Glomerular filtration rate was estimated (eGFR) by CKD‐EPI equation. RTR group (RTRG) and CG presented similar age and BMI. RTRG when compared to CG presented lower percentage of women and eGFR; higher central adiposity; and lower values of reactance, intracellular water, body cell mass and phase angle, more consistently observed in women. This study suggests that overweight RTR present higher abdominal adiposity and impairment in BIA parameters that are sensitive indicators of impaired membrane integrity, water distribution, and body cell mass.

show abstract

Graft function and nutritional parameters in stable post renal transplant patients

Saxena

Sharma

Gupta

2013

Clinical Queries: Nephrology

View full text Add to dashboard Cite

Bioimpedance analysis highlights changes in body composition at the early stages of impairment of kidney transplant function

Cited by 6 publications

References 16 publications

Body Composition Assessed by Impedance Changes Very Early with Declining Renal Graft Function

Body Composition Assessed by Impedance Changes Very Early with Declining Renal Graft Function

High abdominal adiposity and low phase angle in overweight renal transplant recipients

Graft function and nutritional parameters in stable post renal transplant patients

Contact Info

Product

Resources

About