Bioheat transfer problems with spatial or transient heating on skin surface or inside biological bodies

Abstract

A bioheat transfer model with quadratic temperature-dependent thermal conductivity is considered in this work. Applying the Taylor expansion method, we have investigated the bioheat transfer problems with generalized spatial or transient heating both on skin surface and inside the biological bodies. The effect of the temperature-dependent thermal conductivity on the nonlinear temperature distribution is studied. The method used in this paper can be useful to investigate several typical bioheat transfer processes, which are often encountered in cancer hyperthermia, laser surgery, thermal comfort analysis, and tissue thermal parameter estimation.

Improved Thermal Ablation of Tumors Using A Real-Time Local Data Measurement System

“…In this approach, the intended biochip is supposed to monitor in real time a thermal therapy process to kill the tumorous tissue and save the healthy tissue surrounding the target. Because the diffusion of the heat in the tissue continues beyond the tumor boundary, dosimetry has been widely explored as a means of controlling the dose of the delivered power [37,38]. Figure 1 shows an example of a real brain tumor with temperature iso-contour distribution on the tissue using one central heat source.…”