Bioglass/ceria nanoparticle hybrids for the treatment of seroma: a comparative long-term study in rats
Michael-Alexander Pais,
Athanasios Papanikolaou,
Isabel Arenas Hoyos
et al.
Abstract:Background: Seroma formation is a common postoperative complication. Fibrin-based glues are typically employed in an attempt to seal the cavity. Recently, the first nanoparticle (NP)-based treatment approaches have emerged. Nanoparticle dispersions can be used as tissue glues, capitalizing on a phenomenon known as ‘nanobridging’. In this process, macromolecules such as proteins physically adsorb onto the NP surface, leading to macroscopic adhesion. Although significant early seroma reduction has been shown, li… Show more
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