Biogenic synthesis of silver-nanoparticles with the brackish water cyanobacterium <i>Nostoc sphaeroides</i> and assessment of antibacterial activity against urinary tract infecting bacteria

Sahoo, Chita Ranjan; Swain, Surendra; Luke, Alexander Maniangat; Paidesetty, Sudhir Kumar; Padhy, Rabindra N.

doi:10.1080/16583655.2021.2005909

Cited by 8 publications

(8 citation statements)

References 31 publications

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“…The highest concentration at 70 μL of Se NPs exhibited higher zone of inhibition for P. aeruginosa > S. aureus > E. coli > P. vulgaris . Similarly, Ag NPs synthesized using Nostoc sphaeroides (cyanobacterium) were tested against pathogens E. coli and S. aureus , and molecular docking was used to investigate the natural compounds and found that nostocine A exhibited higher binding affinity with the bacterial DNA gyrase . Jana et al used a ligand exchange method to synthesize a virstatin derivative to conjugate with Au NPs.…”

Section: Inhibitory Action Of Nanoparticles Against Microbesmentioning

confidence: 99%

“…346 Similarly, Ag NPs synthesized using Nostoc sphaeroides (cyanobacterium) were tested against pathogens E. coli and S. aureus, and molecular docking was used to investigate the natural compounds and found that nostocine A exhibited higher binding affinity with the bacterial DNA gyrase. 347 Jana et al used a ligand exchange method to synthesize a virstatin derivative to conjugate with Au NPs. The conjugated material affected the bacterial membrane potential studied through the fluorescence of membrane-sensitive cationic dye diSC 3 .…”

Section: Antibacterial Activitymentioning

confidence: 99%

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Recent Advancements in Plant- and Microbe-Mediated Synthesis of Metal and Metal Oxide Nanomaterials and Their Emerging Antimicrobial Applications

Rana

Pathak

Lim

et al. 2023

ACS Appl. Nano Mater.

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Antibiotic resistance against infections caused by microbes has emerged as a global challenge resulting in longer hospitalizations and higher medical cost and mortality. The excessive use of antibiotics has led to the swift progression of antibiotic resistance in bacterial strains. Metallic and metal oxide (M/MO) nanoparticles (NPs) have the potential to provide a pertinent alternative to antibiotics as they interact with the critical cellular organelles and biomolecules such as DNA, enzymes, ribosomes, and lysosomes. This affects the permeability of the cell membrane causing oxidative stress, gene expression, protein activation, and enzyme activation restricting the habitat of microbes. Further, NPs simultaneously target multiple biomolecules at once making them an efficient antibacterial agent against which microbes are unable to develop resistance easily, although the toxicity associated with the M/MO NPs still remains a key challenge for clinical uses. Green synthesis provides an efficient solution to reduce the toxic effects associated with these NPs as it does not use harsh chemicals and environment for the synthesis of NPs. In this work, we have provided a comprehensive review of the green synthesis of M/MO NPs using plants (roots, seeds, barks, flowers) and microbes (bacteria, fungi, algae). The yield of the NPs achieved from the green synthesis is lower than that of conventional methods and significant advancements have been made recently which are delineated in this review for different M/ MO NPs. Further, the mechanism of NP interaction with the microbes and their different antimicrobial applications have been discussed in detailed. The present review aims to provide a critical overview of the current state of the large-scale synthesis of the M/ MO NPs as well as their different antimicrobial activities.

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Section: Inhibitory Action Of Nanoparticles Against Microbesmentioning

confidence: 99%

Section: Antibacterial Activitymentioning

confidence: 99%

Recent Advancements in Plant- and Microbe-Mediated Synthesis of Metal and Metal Oxide Nanomaterials and Their Emerging Antimicrobial Applications

Rana

Pathak

Lim

et al. 2023

ACS Appl. Nano Mater.

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“…Following 24-72 hour incubation at 37 1C AE 1, the inhibition zones were observed and measured by the zone of inhibition scale. [27][28][29][30]…”

Section: Antimicrobial Assaymentioning

confidence: 99%

Evaluation of the antimicrobial potential of cerium-based perovskite (CeCuO₃) synthesized by a hydrothermal method

Soren

Chakroborty²,

Mahalik

et al. 2022

New J. Chem.

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“…The metabolic versatility of cyanobacteria lends them to bioengineering applications for sustainable production of various products ( Stal, 2007 ; Xie et al, 2017 ; Momper et al, 2019 ; Liu et al, 2021 ). Especially, cyanobacteria derived bioactive compounds have a development potential in scientific research and great opportunity for drug discovery ( Vijayakumar and Menakha, 2015 ; Sahoo et al, 2021 ). For example, apratoxin D isolated from cyanobacterium Lyngbya sp.…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, cyanobacteria could also applied in the field of nanotechnology ( Mandhata et al, 2022 , Bishoyi et al, 2023 ). Sahoo et al synthesized silver-nanoparticles (AgNPs) with cyanobacterium Nostoc sphaeroides and explored their antibacterial activity against bacterial strains that could lead urinary tract infection ( Sahoo et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Network pharmacology‒based analysis of marine cyanobacteria derived bioactive compounds for application to Alzheimer’s disease

Xie,

Chen,

et al. 2023

Front. Pharmacol.

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In recent years, the Alzheimer’s disease (AD) epidemic has become one of the largest global healthcare crises. Besides, the available systemic therapies for AD are still inadequate. Due to the insufficient therapeutic options, new treatment strategies are urgently needed to achieve a satisfactory therapeutic effect. Marine bio-resources have been accepted as one of the most economically viable and sustainable sources with potential applications for drug discovery and development. In this study, a marine cyanobacteria–Synechococcus sp. XM-24 was selected as the object of research, to systematically investigate its therapeutic potential mechanisms for AD. The major active compounds derived from the Synechococcus sp. biomass were identified via pyrolysis-gas chromatography-mass spectrometry (GC-MS), and 22 compounds were identified in this strain. The most abundant chemical compounds was (E)-octadec-11-enoic acid, with the peak area of 30.6%. Follow by tridecanoic acid, 12-methyl- and hexadecanoic acid, with a peak area of 23.26% and 18.23%, respectively. GC-MS analysis also identified indolizine, isoquinoline, 3,4-dihydro- and Phthalazine, 1-methyl-, as well as alkene and alkane from the strain. After the chemical toxicity test, 10 compounds were finally collected to do the further analysis. Then, network pharmacology and molecular docking were adopted to systematically study the potential anti-AD mechanism of these compounds. Based on the analysis, the 10 Synechococcus-derived active compounds could interact with 128 related anti-AD targets. Among them, epidermal growth factor receptor (EGFR), vascular endothelial growth factor A (VEGFA) and mitogen-activated protein kinase 3 (MAPK3) were the major targets. Furthermore, the compounds N-capric acid isopropyl ester, (E)-octadec-11-enoic acid, and 2H-Pyran-2,4(3H)-dione, dihydro-6-methyl- obtained higher degrees in the compounds-intersection targets network analysis, indicating these compounds may play more important role in the process of anti-AD. In addition, Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis showed that these active compounds exert the anti-AD effects mainly through PI3K-Akt signaling pathway, neuroactive ligand-receptor interaction and ras signaling pathway. Our study identified Synechococcus-derived bioactive compounds have the potential for application to AD by targeting multiple targets and related pathways, which will provide a foundation for future research on applications of marine cyanobacteria in the functional drug industry.

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Biogenic synthesis of silver-nanoparticles with the brackish water cyanobacterium Nostoc sphaeroides and assessment of antibacterial activity against urinary tract infecting bacteria

Cited by 8 publications

References 31 publications

Recent Advancements in Plant- and Microbe-Mediated Synthesis of Metal and Metal Oxide Nanomaterials and Their Emerging Antimicrobial Applications

Recent Advancements in Plant- and Microbe-Mediated Synthesis of Metal and Metal Oxide Nanomaterials and Their Emerging Antimicrobial Applications

Evaluation of the antimicrobial potential of cerium-based perovskite (CeCuO₃) synthesized by a hydrothermal method

Network pharmacology‒based analysis of marine cyanobacteria derived bioactive compounds for application to Alzheimer’s disease

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Biogenic synthesis of silver-nanoparticles with the brackish water cyanobacterium Nostoc sphaeroides and assessment of antibacterial activity against urinary tract infecting bacteria

Cited by 8 publications

References 31 publications

Recent Advancements in Plant- and Microbe-Mediated Synthesis of Metal and Metal Oxide Nanomaterials and Their Emerging Antimicrobial Applications

Recent Advancements in Plant- and Microbe-Mediated Synthesis of Metal and Metal Oxide Nanomaterials and Their Emerging Antimicrobial Applications

Evaluation of the antimicrobial potential of cerium-based perovskite (CeCuO3) synthesized by a hydrothermal method

Network pharmacology‒based analysis of marine cyanobacteria derived bioactive compounds for application to Alzheimer’s disease

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Evaluation of the antimicrobial potential of cerium-based perovskite (CeCuO₃) synthesized by a hydrothermal method