Biogenic synthesis and antimicrobial activity of silica-coated silver nanoparticles for esthetic dental applications

Rodrigues, Marcela Charantola; Rolim, Wallace R.; Viana, Marina Mariante; Souza, Thaís Rodrigues; Gonçalves, Flávio de Oliveira; Tanaka, Caio Junji; Bueno‐Silva, Bruno; Seabra, Amedea B.

doi:10.1016/j.jdent.2020.103327

Cited by 68 publications

(43 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The influence of AgNPs on the color of composite resins and the potential damage to human health limit its scope of use [ 18 , 43 ]. Rodrigues et al [ 44 ] synthesized AgNPs from green tea extract and coated the AgNPs with silica, resulting in light-colored Ag@SiO 2 nanoparticles. Adding Ag@SiO 2 NPs to the composite resin can prevent the formation of Streptococcus mutans biofilms without compromising esthetics.…”

Section: Current Antimicrobial Strategies Of Resin Compositesmentioning

confidence: 99%

Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives

Sun¹,

Zhang²,

Bai³

et al. 2021

Polymers

View full text Add to dashboard Cite

Repairing tooth defects with dental resin composites is currently the most commonly used method due to their tooth-colored esthetics and photocuring properties. However, the higher than desirable failure rate and moderate service life are the biggest challenges the composites currently face. Secondary caries is one of the most common reasons leading to repair failure. Therefore, many attempts have been carried out on the development of a new generation of antimicrobial and therapeutic dental polymer composite materials to inhibit dental caries and prolong the lifespan of restorations. These new antimicrobial materials can inhibit the formation of biofilms, reduce acid production from bacteria and the occurrence of secondary caries. These results are encouraging and open the doors to future clinical studies on the therapeutic value of antimicrobial dental resin-based restoratives. However, antimicrobial resins still face challenges such as biocompatibility, drug resistance and uncontrolled release of antimicrobial agents. In the future, we should focus on the development of more efficient, durable and smart antimicrobial dental resins. This article focuses on the most recent 5 years of research, reviews the current antimicrobial strategies of composite resins, and introduces representative antimicrobial agents and their antimicrobial mechanisms.

show abstract

Section: Current Antimicrobial Strategies Of Resin Compositesmentioning

confidence: 99%

Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives

Sun¹,

Zhang²,

Bai³

et al. 2021

Polymers

View full text Add to dashboard Cite

show abstract

“…Результаты антимикробного исследования в отношении Streptococcus mutans, бактерий способных вызывать кариес, показали значительное снижение метаболической активности (44 %) при концентрации 600 мкг/мл. Оценка цитотоксичности на фибробластах пульпы зуба в диапазоне МИК 100-600 мкг/л продемонстрировала жизнеспособность клеток от 80-98 %, что позволило сделать вывод об отсутствии токсического эффекта у данных частиц [35]. Таким образом, было показано, что композиты, содержащие антибактериальные агенты, такие как AgNP уменьшают образование кариесогенных биопленок и могут найти полезное применение в стоматологических материалах.…”

Section: материалы студенческой научной школыunclassified

Biomedical Applications of Silver Nanoparticles (Review)

Реджепов

Водяшкин

Сергородцева

et al. 2021

Razrabotka i registraciâ lekarstvennyh sredstv

View full text Add to dashboard Cite

Introduction. Silver nanoparticles have unique physicochemical properties and can be used for the diagnosis and treatment of various kinds of infections, oncological diseases, as well as drug delivery. The review presents an analysis of scientific literature on the use of silver nanoparticles for biomedical purposes.Text. The review discusses the perspectives of the silver nanoparticles use in the treatment of oncological diseases as a carrier of drugs, as well as the direct manifestation of their cytotoxic effect on cancer cells. Also, there is considered the use of silver nanoparticles for imparting or enhancing the antibacterial effects of dressings and dental materials. The mechanism of action of silver nanoparticles against viruses is considered. This research presents the use of composite materials containing silver nanoparticles for biomedical purposes.Conclusion. On the basis of the literature data analysis, carried out by the authors, there are shown possibilities of the nanotechnology achievements for the application in medicine.

show abstract

“…Therefore, there is a need to use drugs with pronounced detoxification properties and prolonged duration of action-these are exactly the properties of drugs immobilized on HDS. The use of HDS for drug immobilization provides a solution to the problem of uniform distribution of small amounts of biologically active substances in the system, and allows for extension of their duration of action [54][55][56]. Several biologically active drugs immobilized on HDS and intended for the treatment of acute deep caries and periodontal tissue diseases have been clinically tested.…”

Section: The Use Of Silica In Medical Practice As a Basis For Theranosticsmentioning

confidence: 99%

The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms

et al. 2021

View full text Add to dashboard Cite

This review presents the main patterns of synthesis for theranostics platforms. We examine various approaches to the interpretation of theranostics, statistics of publications drawn from the PubMed database, and the solid-state and medicinal chemistry methods used for the formation of nanotheranostic objects. We highlight and analyze chemical methods for the modification of nanoparticles, synthesis of spacers with functional end-groups, and the immobilization of medicinal substances and fluorophores. An overview of the modern solutions applied in various fields of medicine is provided, along with an outline of specific examples and an analysis of modern trends and development areas of theranostics as a part of personalized medicine.

show abstract

Biogenic synthesis and antimicrobial activity of silica-coated silver nanoparticles for esthetic dental applications

Cited by 68 publications

References 48 publications

Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives

Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives

Biomedical Applications of Silver Nanoparticles (Review)

The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms

Contact Info

Product

Resources

About