Biogenic magnetite nanoparticles: A potent and environmentally benign agent for efficient removal of azo dyes and phenolic contaminants from water

Facile, rapid and efficient isolation of circulating tumor cells using aptamer-targeted magnetic nanoparticles integrated with a microfluidic device

“…The biocompatibility of MNPs was first studied on the HUVEC and MCF-7 breast cancer cells by MTT assay, according to the previous report. 51 Briefly, 10 4 cells were added into each well of a 96-well plate containing 200 μL RPMI 1640 medium supplemented with 10% FBS and 1% antibiotic solution and incubated in a humidified incubator at 37 °C under 5% CO 2 . After 24 h, different concentrations of MNPs (0, 5, 10, 20, 50, and 100 μg mL −1 ) were added into the individual wells and incubated again for 48 h in the same condition.…”

Combined Ibuprofen-Nanoconjugate Micelles with E-Selectin for Effective Sunitinib Anticancer Therapy

“…5 mg/mL MTT solution was immediately added each well and incubated at 37℃ for another 4 hours. 44 After removing the medium from each well, 200 µL DMSO was added and agitated for 15 minutes. Absorption at 490 nm was measured using microplate reader (Infinite F200 PRO, TECAN, AUSTRIA).…”

Recent Advances in Nanomaterials Development for Nanomedicine and Cancer

“…Among them, gold NPs have found extensive applications for bioimaging, biosensing, and therapy. − Despite the significant advances in the surface modification of these NPs, new approaches need to be developed to overcome this challenge. In this regard, the green synthesis approach has been considered for the synthesis of different inorganic NPs such as gold, silver, iron oxide, copper oxide, and zinc oxide. − The biogenic methods are mainly based on the nontoxic solvents and biological compounds instead of the currently used toxic chemicals for the synthesis of NPs . This eco-friendly and straightforward approach is currently used to effectively synthesize NPs with new and interesting biological properties such as antibacterial, antifungal, antiviral, anticancer, and antioxidant activities. ,, These interesting activities are mainly originated from the organic compounds commonly used as the reducing and stabilizing agents in the green synthesis of NPs.…”

“…In this regard, the green synthesis approach has been considered for the synthesis of different inorganic NPs such as gold, silver, iron oxide, copper oxide, and zinc oxide. − The biogenic methods are mainly based on the nontoxic solvents and biological compounds instead of the currently used toxic chemicals for the synthesis of NPs . This eco-friendly and straightforward approach is currently used to effectively synthesize NPs with new and interesting biological properties such as antibacterial, antifungal, antiviral, anticancer, and antioxidant activities. ,, These interesting activities are mainly originated from the organic compounds commonly used as the reducing and stabilizing agents in the green synthesis of NPs. Synthesis of different inorganic NPs with the controlled size, shape, and other physicochemical properties obtained by this approach simply occurs via the use of different concentrations of various biogenic compounds .…”

“…Metal-based NPs are widely used in biomedicine due to their advantages, including facile synthesis with the controlled sizes and shapes, easy surface functionalization, high biocompatibility, and attractive physicochemical properties. , Noble metal NPs of gold and silver are among the most widely used metal NPs for biomedical applications. The biocompatible gold NPs are extensively considered for their optical properties in biosensing , and as a nanocarrier for drug delivery. , The silver NPs are mainly used as the antimicrobial agents against bacterial, fungal, and viral contaminants. − The anticancer activity of silver NPs and their action mechanisms against the cancer cell lines have also been reported. , The superparamagnetic iron oxide NPs (SPIONs) are one of the most commonly used NPs in the applied sciences due to their excellent properties, especially the simple and cost-effective synthesis, prominent magnetic activity, and easy functionalization. , The biocompatible and superparamagnetic SPIONs are extensively used in biomedical applications such as magnetically conducted drug delivery, gene delivery, biosensing, , imaging, − diagnostics, , therapy, and the magnetic separation of biological targets. − The most common applications of SPIONs in biomedicine include magnetic resonance imaging (MRI), immunomagnetic separation, and hyperthermia.…”