Biofilm Formation of Acinetobacter baumannii Under in vitro and in vivo Colistin Exposure

Abstract

A cinetobacter baumannii is one of the most pathogenic nosocomial infection agents because of its extreme resistance to almost all known antibiotics and host immune responses (1). The emergence of colistin-resistance in A. baumannii has been reported throughout the world (2, 3). Biofilm formation ability enhances virulence of A. baumannii by increasing survival of cells in unfavourable environmental conditions, such as underexposure of disinfectants, antibiotics or attack of immune cells (4, 5). Antibiotic-resistant phenotypes This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License.