Biofilm Bacteria Plays a Role in Csom Pathogenesis and Has Significant   Correlation With Unsafe Type Csom

Artono, Artono; Purnami, Nyilo; Rahmawati, Rosydiah

doi:10.20473/fmi.v51i4.2846

Cited by 5 publications

(3 citation statements)

References 11 publications

(14 reference statements)

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“…Biofilm juga telah ditunjukkan pada mukosa telinga tengah anak-anak dengan otitis media kronis, dan pada efusi telinga tengah dari anak-anak dengan otitis media akut berulang yang kemungkinan merupakan faktor risiko untuk OMSK. 13,14 Biofilm merupakan koloni bakteri yang tumbuh perlahan dan dibungkus suatu lapisan glikopolisakarida yang disebut glycocalyx. Ikatan bakteri dengan permukaan host membentuk biofilm.…”

Section: Pembahasanunclassified

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Bakteri Penyebab Otitis Media Supuratif Kronis di Rumah Sakit Umum Universitas Kristen Indonesia

Parhusip

Utomo

Marlina

et al. 2021

MK-UKI

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Abstrak Otitis media supuratif kronis (OMSK) merupakan inflamasi dari telinga tengah dan rongga mastoid kronis, ditandai dengan perforasi membran timpani serta cairan yang keluar dari telinga secara persisten. Gangguan pendengaran dan kecacatan umumnya disebabkan oleh OMSK. Komplikasi otitis media supuratif kronis lainnya dapat menyebabkan infeksi intrakranial yang fatal dan mastoiditis akut, terutama di Negara-negara berkembang. Penatalaksanaan yang efektif tergantung pada pengetahuan mengenai mikroorganisme penyebab dan sensitivitas mikroba. Penelitian ini bertujuan untuk mengetahui pola bakteri penyebab otitis media supuratif kronis di Rumah Sakit Umum Universitas Kristen Indonesia Tahun 2019. Metode penelitian yang digunakan adalah deskriptif dengan pendekatan secara clinical series yang dilakukan dari bulan Agustus 2019 sampai November 2019 di Poliklinik THT-KL RSU UKI dan Laboratorium Mikrobiologi FK UKI. Hasil dari 17 sampel menunjukkan bahwa Staphylococcus aureus merupakan bakteri terbanyak yang ditemukan pada penderita OMSK yaitu 6 (35,3%), diikuti Pseudomonas aerugenosa 5 (29,4%), Staphylococcus epidermidis 2 (11,8%), Klebsiella spp. 2 (11,8%), Proteus spp. 1 (5,9%), Escherichia coli 1 (5,9%). Kata kunci :otitis media supuratif kronis, pola bakteri. Abstract Chronic suppurative otitis media (CSOM) is a chronic inflammation of the middle ear and mastoid cavity, followed with recurrent ear discharges or otorrhoea through a tympanic perforation. Hearing impairment and disability are generally caused by CSOM. Other complications of chronic suppurative otitis media can lead to fatal intracranial infections and acute mastoiditis, especially in developing countries. Effectivity of the disease management depends on the knowledge of causative microorganisms and their antimicrobial sensitivity. The purpose of this study is to identify the bacterial pattern that cause chronic suppurative otitis media in Christian University of Indonesia General Hospital in 2019. This study is using the descriptive method with a clinical series approach, this study was carried out from August 2019 to November 2019 at the polyclinic of ENT-HNS RSU UKI and Microbiology Laboratory FK UKI. The results of 17 samples showed Staphylococcus aureus was the most bacteria found in CSOM patient 6 samples (35,3%), followed Pseudomonas aerugenosa 5 (29,4%), Staphylococcus epidermidis 2 (11,8%), Klebsiella spp. 2 (11,8%), Proteus spp. 1 (5,9%), Escherichia coli 1 (5,9%). Keywords: chronic suppurative otitis media, bacterial pattern

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Section: Pembahasanunclassified

“…Hal ini menunjukkan bakteri biofilm memiliki hubungan bermakna dengan OMSK tipe bahaya. 13 Pada tabel diatas dapat diketahui Klebsiella spp. berjumlah 2 (11,8%), Proteus spp., Escherichia coli masing-masing memiliki jumlah yang sama yaitu 1 (5,9%).…”

Section: Pembahasanunclassified

Bakteri Penyebab Otitis Media Supuratif Kronis di Rumah Sakit Umum Universitas Kristen Indonesia

Parhusip

Utomo

Marlina

et al. 2021

MK-UKI

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“…Whereas the canal wall up technique (CWU) is performed by cleaning all pathological tissue while maintaining the posterior meatal, so on the contrary, the mastoid cavity is not left open. 8 Canal wall reconstruction (CWR) tympanomastoidectomy is a technique that combines CWD and CWU with the purpose of optimizing eradication of cholesteatoma tissue, and providing blockade of the attic, thereby reducing the risk of recurrence and formation of retraction pockets. The CWR technique was introduced by Mercke in 1987 and is performed with mastoid obliteration using several methods such as osteoperiosteal flaps, ceramic alloplasts, bone cements, and costal cartilage.…”

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confidence: 99%

Management of recurrent chronic suppurative otitis media with cholesteatoma

Christianty,

Wahyudiono

2023

Oto Rhino Laryn Indones

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Background: Chronic suppurative otitis media (CSOM) is a chronic inflammation involving the middle ear space and it became a burden especially in developing countries. Mastoidectomy remains the main treatment in CSOM with cholesteatoma. Recurrent cholesteatoma and suppurating process indicated the need of revision mastoidectomy. Purpose: Until now, study about the mechanism of recurrent cholesteatoma and its management still need further research. Case report: This paper reports a case of chronic suppurative otitis media with recurrent cholesteatoma which underwent revision mastoidectomy. Clinical Question : What are the factors associated with the occurrence of recurrent cholesteatoma and how to managed it? Methods: Evidence base literature study about chronic suppurative otitis media with recurrent cholesteatoma and surgery treatment was performed through PubMed, ProQuest, and Google Scholar database. Results: Recurrent cholesteatoma that occurred after mastoidectomy can be caused by residue of the cholesteatoma itself or new forming of retraction pocket. Revision mastoidectomy is necessary to evacuated the cholesteatoma and provide good drainage to the mastoid. Conclusion: Routine follow up after mastoidectomy is an important thing to help prevent recurrence of CSOM especially with cholesteatoma.

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The Association of IL-1 Alpha Level and TNF Alpha Expressions on Bone Destruction in Chronic Suppurative Otitis Media and Cholesteatoma

Artono

Surarto

Purnami

et al. 2019

Indian J Otolaryngol Head Neck Surg

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Biofilm Bacteria Plays a Role in Csom Pathogenesis and Has Significant Correlation With Unsafe Type Csom

Cited by 5 publications

References 11 publications

Bakteri Penyebab Otitis Media Supuratif Kronis di Rumah Sakit Umum Universitas Kristen Indonesia

Bakteri Penyebab Otitis Media Supuratif Kronis di Rumah Sakit Umum Universitas Kristen Indonesia

Management of recurrent chronic suppurative otitis media with cholesteatoma

The Association of IL-1 Alpha Level and TNF Alpha Expressions on Bone Destruction in Chronic Suppurative Otitis Media and Cholesteatoma

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