Biofabrication of graphene QDs as a fluorescent nanosensor for detection of toxic and heavy metals in biological and environmental samples

Khan, Fahmida; Pattanayak, Subrat Kumar; Verma, Padma Rani; Dewangan, Pradeep Kumar

doi:10.1016/b978-0-12-820781-9.00008-5

Cited by 7 publications

(4 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Accumulating Uranium causes lung, bone, and thyroid cancer in humans. Sometimes higher intakes result in acute renal failure and even death [163][164][165] . Its concentration builds up in the human body's organs and tissues, posing various health risks 166,167 .…”

Section: Uranium Toxicity In Humanmentioning

confidence: 99%

Uranium Sources, Uptake, Translocation in the soil-plant System and Its Toxicity in Plants and Humans: A Critical Review

et al. 2023

View full text Add to dashboard Cite

Uranium(U) is one of the highly toxic heavy metals and radionuclides that has become a major threat to soil health. There are two types of sources of Uranium in the soil system, natural and anthropogenic. Natural sources of uranium include rock systems and volcanic eruptions while anthropogenic sources include mining activities, disposal of radioactive waste, application of phosphate fertilizers, etc. Uranium accumulation impacts germination, early seedling growth, photosynthesis, metabolic and physiological processes of the plants. Through its accumulation in the aerial parts of the plants, Uranium finds its way to the human body, where it has deleterious health impacts. Different studies have identified the various sources of Uranium, explored, and explained the geochemistry of Uranium in soil, assessed the Uranium uptake and toxicity to the plants, and further studied the impact on human health. Most studies focused on two stages, either soil-plant or plant-human system. However, few studies have critically reviewed and summarized the U in the soil-plant-human system. Thus, the review has been designed to focus on the sources, geochemical behaviour, uptake, and translocation, plant toxicity, food chain entry, and finally, impact on human health. The relationship between the bioavailability of Uranium in the soil-plant system with soil properties like pH, Organic matter, and microorganisms have also been included. The study is further intensified by analyzing the accumulation of Uranium in various parts of the plants.

show abstract

Section: Uranium Toxicity In Humanmentioning

confidence: 99%

Uranium Sources, Uptake, Translocation in the soil-plant System and Its Toxicity in Plants and Humans: A Critical Review

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Exposure to them leads to cardiovascular diseases, cancer mortality, neurological disorders, etc. [6]. Table 1 explains the harmful health effects of various heavy metals.…”

Section: Introduction 11 Heavy Metal Pollutionmentioning

confidence: 99%

Metal-Organic-Frames (MOFs) Based Electrochemical Sensors for Sensing Heavy Metal Contaminated Liquid Effluents: A Review

et al. 2022

View full text Add to dashboard Cite

Toxic heavy metal ions may have adverse health effects on human health. sensing and effective removal is an important issue. Metal-organic frameworks (MOFs) are a novel group of crystalline porous materials. Because of their extremely high surface areas, optimized pore volumes and pore size distributions for specific detection, electrochemical sensors based on MOF's are gaining popularity. They are reliable, easy to use and have good sensitivity. This review will give an insight into the selection of MOF's as heavy metal sensing devices and the mechanism behind the detection of specific metal ions shall also be explained. Challenges and prospects for practical applications of MOFs in heavy metal ion detection will be also discussed.

show abstract

“…Fluorescent biosensors have a wide range of implications, and the analyse of heavy metal ions is one. Heavy metal ions are non-biodegradable substances that can cause particular harm to the human body and environment through accumulation [2]. Heavy metal ions can be converted into metal toxins within the body or the food chain, hindering metabolic processes [3].…”

Section: Introductionmentioning

confidence: 99%

“…Yet these methods hold limitations for stability, selectivity, and detection limits with aqueous solutions. Attention has been turned towards optical detection methods, especially fluorescence biosensors, with their prominent features in simplicity, selectivity, and low-detection limits [2].…”

Section: Introductionmentioning

confidence: 99%

Application of fluorescent biosensors for heavy metal ions detection

Xu¹

2022

HSET

View full text Add to dashboard Cite

Heavy metal ions can be successfully detected by using a diverse of the developed fluorescent biosensors. A major trend in designing current fluorescent biosensors incorporates nanomaterials, such as quantum dots. Combined techniques with aptamers allow for highly sensitive analyses of different heavy metal ions. Other novel methods of detection involve whole cells, for example, bacterial bioreporters. A common way of exhibiting fluorescence is through “signal-on” and “signal-off”, where some fluorescent biosensors may depend on only one state, others rely on both states of emission. The methods detecting mercury ions listed include mercury-specific oligonucleotide (MSO) probes and a dual emission ratiometric fluorescent probe using silicon (SiNPs) or gold nanoclusters (AuNCs). Methods mentioned for arsenic ions include two different kinds of fluorescent-based aptasensors and a fluorescent DNA quantum dot. As to lead ions, a fluorescent method that utilizes the interactions between DNA aptamer, acridine orange, and nanomaterials is designed. Another method is through quantum dots and DNAzyme synergetic catalytic amplification. For cadmium ions, a whole-cell bioreporter was developed that incorporated bacterial organisms. All recently published methods shared a commonality of exceptional sensitivity and selectivity.

show abstract

Biofabrication of graphene QDs as a fluorescent nanosensor for detection of toxic and heavy metals in biological and environmental samples

Cited by 7 publications

References 47 publications

Uranium Sources, Uptake, Translocation in the soil-plant System and Its Toxicity in Plants and Humans: A Critical Review

Uranium Sources, Uptake, Translocation in the soil-plant System and Its Toxicity in Plants and Humans: A Critical Review

Metal-Organic-Frames (MOFs) Based Electrochemical Sensors for Sensing Heavy Metal Contaminated Liquid Effluents: A Review

Application of fluorescent biosensors for heavy metal ions detection

Contact Info

Product

Resources

About