Biofabrication of ecofriendly copper oxide nanoparticles using Ocimum americanum aqueous leaf extract: analysis of in vitro antibacterial, anticancer, and photocatalytic activities

Manikandan, Dinesh Babu; Arumugam, Manohar; Veeran, Srinivasan; Sridhar, Arun; Sekar, Rajkumar Krishnasamy; Balaji, Perumalsamy; Ramasamy, Thirumurugan

doi:10.1007/s11356-020-12108-w

Cited by 27 publications

(14 citation statements)

References 68 publications

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“…(Ali et al 2021;Pandey et al 2014;Purushothaman et al 2018;Santos et al 2021;Singh and Chaudhuri 2018;Singh et al 2015Singh et al , 2016, whereas essential oil is valued in aromatherapy (Li and Chang 2016). On the other hand, silver and copper nanoparticles synthesized using aqueous leaf extract of O. americanum have shown therapeutic properties, including in vitro antibacterial, anticancer and catalytic properties, which can be used for photocatalytic dye degradation (Manikandan et al 2021a, b). Recently, a molecular docking study showed that apigenin, oleanolic acid and ursolic acid from O. basilicum are potential inhibitors of chymotrypsin-like protease of severe acute respiratory syndrome coronavirus (SARS-CoV2) and could be effective in the treatment of coronavirus disease (COVID-19) (Matondo et al 2021).…”

Section: Introductionmentioning

confidence: 99%

A glance at the chemodiversity of Ocimum species: Trends, implications, and strategies for the quality and yield improvement of essential oil

2021

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Ocimum species represent commercially important medicinal and aromatic plants. The essential oil biosynthesized by Ocimum species is enriched with specialized metabolites specifically, terpenoids and phenylpropanoids. Interestingly, various Ocimum species are known to exhibit diverse chemical profiles, and this chemical diversity has been at the center of many studies to identify commercially important chemotypes. Here, we present various chemotypes from the Ocimum species and emphasize trends, implications, and strategies for the quality and yield improvement of essential oil. Globally, many Ocimum species have been analyzed for their essential oil composition in over 50 countries. Asia represents the highest number of chemotypes, followed by Africa, South America, and Europe. Ocimum basilicum L. has been the most widespread and well-studied species, followed by O . gratissimum L., O . tenuiflorum L., O . canum Sims, O . americanum and O . kilimandscharicum Gürke. Moreover, various molecular reasons, benefits, adverse health effects and mechanisms behind this vast chemodiversity have been discussed. Different strategies of plant breeding, metabolic engineering, transgenic, and tissue-culture, along with anatomical modifications, are surveyed to enhance specific chemotypic profiles and essential oil yield in numerous Ocimum species. Consequently, chemical characterization of the essential oil obtained from Ocimum species has become indispensable for its proper utilization . The present chemodiversity knowledge from Ocimum species will help to exploit various applications in the industrial, agriculture, biopharmaceutical, and food sectors. Supplementary Information The online version contains supplementary material available at 10.1007/s11101-021-09767-z.

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Section: Introductionmentioning

confidence: 99%

A glance at the chemodiversity of Ocimum species: Trends, implications, and strategies for the quality and yield improvement of essential oil

2021

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“…Also, Sharma and Dutta [ 110 ] showed that hydroxyl radicals formed to take part in the degradation when applying CuO NPs as catalysts. Overall, compared to CuO NPs synthesized using other plant extracts [ [111] , [112] , [113] , [114] , [115] , [116] , [117] , [118] , [119] , [120] ], the biosynthesized LI-CuO NPs exhibited superior performance in degrading MB dye ( Table 2 ). However, it's noteworthy that the photocatalytic activity of metallic nanoparticles is influenced by different factors including reaction time, concentration, morphology, shape and size of the particles [ 77 , 121 , 122 ].…”

Section: Resultsmentioning

confidence: 99%

Multi-functional copper oxide nanoparticles synthesized using Lagerstroemia indica leaf extracts and their applications

Geremew,

Palmer,

Johnson

et al. 2024

Heliyon

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“…The smaller size of NPs correlates with the higher toxic effects on microorganisms, which have relatively large interfacial area thereby increasing their antibacterial effectiveness 34 . In our previous reports, the size distribution (DLS) of the AgNPs, 27 CuONPs, 28 and Ag‐CuO NCs 29 was discussed. The broad XRD peaks clearly indicated the purity of the green fabricated AgNPs, CuONPs, and Ag‐CuO NCs.…”

Section: Resultsmentioning

confidence: 99%

“…33 The smaller size of NPs correlates with the higher toxic effects on microorganisms, which have relatively large interfacial area thereby increasing their antibacterial effectiveness. 34 In our previous reports, the size distribution (DLS) of the AgNPs, 27 CuONPs, 28 and Ag-CuO NCs 29 HR-TEM analysis of green synthesized AgNPs showed spherical in shape, 27 CuONPs showed in spherical and rod shape, 28 and the Ag-CuO NCs showed intercalate to AgNPs and CuONPs, as spherical and rod-shaped structure. 29 The fluorescence studies were carried out for the prepared NPs; thus, AgNPs, CuONPs, and Ag-CuO NCs are apparently having good optical as well as biological properties.…”

Section: Physicochemical Characterizationmentioning

confidence: 86%

Green synthesized AgNPs, CuONPs, and Ag‐CuO NCs to effective antibiofilm activities and their potential application in aquaculture

Manikandan,

Arumugam,

Abdul

et al. 2023

Applied Organom Chemis

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The expanded emergence of drug‐resistant microbes remains a concern to the scientific community in developing effective therapeutics. Approach of green chemistry based nanomaterials fabrication is in high demand, due to biocompatibility, non‐toxic, and high surface area that adheres more biomolecules on surface. Green fabricated silver nanoparticles (AgNPs), copper oxide nanoparticles (CuONPs), and silver–copper oxide nanocomposites (Ag‐CuO NCs) were characterized by fluorescence and Raman spectroscopy, field emission scanning electron microscopy (FE‐SEM) with energy‐dispersive X‐ray spectroscopy (EDX), and thermogravimetric (TG)/differential scanning calorimetry (DSC) analysis. Antibiofilm potential of green fabricated AgNPs, CuONPs, and Ag‐CuO NCs was tested against aquatic pathogenic microorganisms such as Aeromonas hydrophila, Pseudomonas aeruginosa, and Staphylococcus aureus. This present study deals with bacterial growth rate, biofilm inhibition, and antibiofilm architecture of AgNPs, CuONPs, and Ag‐CuO NCs under the visualization of confocal laser scanning electron microscopy (CLSM). The FE‐SEM technique was used to observe dense and compact structure (control without NPs treatment) with treatment of NPs that showed reduced amount of cell population in A. hydrophila, P. aeruginosa, and S. aureus. The effective antibiofilm inhibition of Ag‐CuO NCs was achieved by reducing micro‐colonies compared with AgNPs and CuONPs. The AgNPs, CuONPs, and Ag‐CuO NCs demonstrated antibiofilm properties against Gram‐negative and Gram‐positive bacteria, indicating a combinatorial effect of green fabricated NPs in combination with plant metabolites against pathogenic bacteria. As a result, aforementioned nano‐product merits further investigation in order to be used as a potent adjuvant therapy as antagonistic toward various bacterial diseases in aquaculture.

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Biofabrication of ecofriendly copper oxide nanoparticles using Ocimum americanum aqueous leaf extract: analysis of in vitro antibacterial, anticancer, and photocatalytic activities

Cited by 27 publications

References 68 publications

A glance at the chemodiversity of Ocimum species: Trends, implications, and strategies for the quality and yield improvement of essential oil

A glance at the chemodiversity of Ocimum species: Trends, implications, and strategies for the quality and yield improvement of essential oil

Multi-functional copper oxide nanoparticles synthesized using Lagerstroemia indica leaf extracts and their applications

Green synthesized AgNPs, CuONPs, and Ag‐CuO NCs to effective antibiofilm activities and their potential application in aquaculture

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