BioEssays 12/2019

Abstract

Gene editing with engineered nucleases introduce double‐strand breaks that are repaired by error‐prone nonhomologous end‐joining (NHEJ). In article number 1900126, Sara G. Trimidal et al. propose that the length and type or resulting indels can now be controlled by editing with different engineered nucleases or by manipulating the expression of NHEJ genes.