Bioenergetics of pregnancy and lactation in European common vole

Migula, P.

doi:10.4098/at.arch.69-13

Cited by 136 publications

(86 citation statements)

References 5 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The lack of an increased food intake during pregnancy in Per2 mutant females may be explained by their high rate of post-implantation embryonic death, but we cannot exclude a statistical error due to the low sample size leading to a high standard error. The control group showed a continuous increase in food consumption in all three stages, similar to reports for pregnant common voles (Migula 1969).…”

Section: Energetic Investment Of Females and Maternal Behavioursupporting

confidence: 70%

“…The period of pregnancy is characterised by an increase in metabolic rate related to rapid growth of the embryos, causing an enhancement in energy intake by the female (Trojan & Wojciechowska 1968, Migula 1969, Degen et al 2002, Johnston et al 2006. However, Per2 mutant females did not significantly increase their food intake during pregnancy, while Per1 mutant females exhibited an increase in food consumption during midterm pregnancy.…”

Section: Energetic Investment Of Females and Maternal Behaviourmentioning

confidence: 99%

See 1 more Smart Citation

Low reproductive success in Per1 and Per2 mutant mouse females due to accelerated ageing?

Pilorz¹,

Steinlechner²

2008

Reproduction

View full text Add to dashboard Cite

Recent studies on mice with mutations in the Clock gene have shown that this mutation disrupts oestrus cyclicity and interferes with successful pregnancy. In order to determine whether two other molecular components of the main clock, namely the period genes, Per1 and Per2, have an effect on the length of the oestrous cycle and the reproductive success, we used Per1-and Per2-deficient females. We show that although fecundity of young adult Per mutant females does not differ from that of wild-type females, middle-aged Per mutant mice are characterised by lower reproductive success than the control group. This may be a consequence of irregularity and acyclicity of the oestrous cycle of the middle-aged mutants. Besides, we demonstrate that Per mutant females have significantly more embryonal implantations in the uterus than successfully delivered offspring. The reproductive deficits of the middle-aged Per mutant females are comparable with those seen in aged wild-type mice. This suggests that Per1 and Per2 mutations cause an advanced ageing.Reproduction (2008) 135 559-568

show abstract

Section: Energetic Investment Of Females and Maternal Behavioursupporting

confidence: 70%

Section: Energetic Investment Of Females and Maternal Behaviourmentioning

confidence: 99%

Low reproductive success in Per1 and Per2 mutant mouse females due to accelerated ageing?

Pilorz¹,

Steinlechner²

2008

Reproduction

View full text Add to dashboard Cite

show abstract

“…Independent food intake by pups during this period is small (this study) (see also Migula, 1969). Pups also start thermo-regulating from day 10 of lactation onwards, and reach full adult thermoregulatory capacity gradually between days 13 and 17 of lactation (Bashenina, 1960).…”

Section: Pup Growthmentioning

confidence: 99%

Ambient temperature shapes reproductive output during pregnancy and lactation in the common vole (Microtus arvalis): a test of the heat dissipation limit theory

Simons

Reimert

Vinne

et al. 2011

Journal of Experimental Biology

View full text Add to dashboard Cite

SUMMARYThe heat dissipation limit theory suggests that heat generated during metabolism limits energy intake and, thus, reproductive output. Experiments in laboratory strains of mice and rats, and also domestic livestock generally support this theory. Selection for many generations in the laboratory and in livestock has increased litter size or productivity in these animals. To test the wider validity of the heat dissipation limit theory, we studied common voles (Microtus arvalis), which have small litter sizes by comparison with mice and rats, and regular addition of wild-caught individuals of this species to our laboratory colony ensures a natural genetic background. A crossover design of ambient temperatures (21 and 30°C) during pregnancy and lactation was used. High ambient temperature during lactation decreased milk production, slowing pup growth. The effect on pup growth was amplified when ambient temperature was also high during pregnancy. Shaving fur off dams at 30°C resulted in faster growth of pups; however, no significant increase in food intake and or milk production was detected. With increasing litter size (natural and enlarged), asymptotic food intake during lactation levelled off in the largest litters at both 21 and 30°C. Interestingly, the effects of lactation temperature on pup growth where also observed at smaller litter sizes. This suggests that vole dams trade-off costs associated with hyperthermia during lactation with the yield from investment in pup growth. Moreover, pup survival was higher at 30°C, despite lower growth, probably owing to thermoregulatory benefits. It remains to be seen how the balance is established between the negative effect of high ambient temperature on maternal milk production and pup growth (and/or future reproduction of the dam) and the positive effect of high temperatures on pup survival. This balance ultimately determines the effect of different ambient temperatures on reproductive success.

show abstract

“…The more extensive home ranges of old individuals may also be of significance. In addition sexually active individuals have greater requirements for high-calorie animal food, that is, for protein and fatty food (Kaczmarski, 1966;Migula, 1969). Greater food consumption of sexually active mice was also observed by Holisova (1967).…”

Section: Discussionmentioning

confidence: 70%