Bioeffects of moderate-intensity static magnetic fields on cell cultures

Dini, Luciana; Abbro, Luigi

doi:10.1016/j.micron.2004.12.009

Cited by 253 publications

(165 citation statements)

References 156 publications

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“…30 The effects depended on the conditions, such as the duration of the exposure, magnetic density, and type of cell. In a previous report, in which these conditions were similar to those in our present study, an exposure of 4.75 T for up to 48 h had no proliferative, activating, or proinflammatory effects on peripheral blood MNCs.…”

Section: Discussionmentioning

confidence: 99%

Magnetic Targeting of Human Peripheral Blood CD133⁺Cells for Skeletal Muscle Regeneration

Ohkawa

Kamei²,

Kamei³

et al. 2013

Tissue Engineering Part C: Methods

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Skeletal muscle injuries often leave lasting functional damage or pain. Muscle injuries are routinely treated conservatively, but the most effective treatment to promote the repair of injured muscles has not yet been established. Our previous report demonstrated that human peripheral blood-derived CD133+ cell transplantation to rat skeletal muscle injury models inhibited fibrosis and enhanced myogenesis after injury. However, the acquisition of a sufficient number of cells remains the limitation for clinical application, as the CD133 + population is rare in human blood. In this study, we applied a magnetic cell targeting system to accumulate transplanted cells in the muscle injury site and to enhance the regenerative effects of CD133 + cell transplantation, focusing on the fact that CD133 + cells are labeled with a magnetic bead for isolation. For the magnetic cell targeting, the magnet field generator was set up to adjust the peak of the magnetic gradient to the injury site of the tibialis anterior muscle, and 1 · 10 4 human peripheral blood CD133 + cells were locally injected into the injury site. This cell number is 10% of that used in the previous study. In another group, the same number of CD133 + cells was injected without magnetic force. The CD133 + cells transplanted with the magnetic force were more accumulated in the muscle injury site compared with the CD133 + cells transplanted without the magnetic force. In addition, the transplantation of CD133+ cells under the magnetic control inhibited fibrous scar formation and promoted angiogenesis and myogenesis, and also upregulated the mRNA expression of myogenic transcription factors, including Pax7, MyoD1 and Myogenin. However, the transplantation of CD133 + cells without the magnetic force failed to demonstrate these effects. Thus, our magnetic cell targeting system enables transplantation of a limited number of CD133 + cells to promote the repair of skeletal muscle injury.

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Section: Discussionmentioning

confidence: 99%

Magnetic Targeting of Human Peripheral Blood CD133⁺Cells for Skeletal Muscle Regeneration

Ohkawa

Kamei²,

Kamei³

et al. 2013

Tissue Engineering Part C: Methods

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“…These treatments can be developed as alternative or at least as an adjunctive treatment for some infectious diseases and chronic wound [2].Static MFs showed inhibiting effects over different bacterial pathogens. One of the theories that can explain the inhibiting and fatal effects of SMFs on living organisms and cells is membrane theory [48][49][50][51][52][53]. This theory explains that the diamagnetic properties of membrane phospholipids determine the effects of SMF on living organisms.…”

Section: Antimicrobial Effects Of Emfmentioning

confidence: 99%

Magnetic Water Treatment in Environmental Management: A Review of the Recent Advances and Future Perspectives

Yadollahpour¹,

Rashidi²,

Rezaee³

et al. 2014

Curr World Environ

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Magnetic water treatment (MWT) is a relatively new technique in environmental management. Magnetic field exposure alters physical and chemical properties of water molecules resulting in unique characteristics.Magnetized water has shown various properties with possible applications in different fields of environmental management. Scale prevention/elimination, soil enhancement, plant growth, crop yield, water saving, and wastewater treatment are some of these applications. Magnetic treatment of water restructures the water molecules into tiny, uniform and hexagonally structured cluster easing their travel through the passageways in plant and animal cell membranes. In addition, toxic agents cannot enter the MW structure. These features make MW a bio-friendly compound for plant and animal cells. The present study reviews the applications of MWT in environmental management. The recent advances of MWT in different fields of environment management are discussed. In addition, the mechanism of action of MWT in different applications and future perspectives are discussed.

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“…According to these experiments and other studies that have emphasized the effect of moderate-intensity SMF from 1mT to 1T on many biological functions [10]. It was tried to determine the effects of a moderate intensity permanent magnetic ield in mT levels on cartilage repair in an animal model.…”

Section: The Effects Of Emf ( Electromagnetic Fields) On the Bone Andmentioning

confidence: 99%

“…It was tried to determine the effects of a moderate intensity permanent magnetic ield in mT levels on cartilage repair in an animal model. It is hypothesizedthat permanent magnetic ields would improve cartilage defect healing and matrix production [10].…”

Section: The Effects Of Emf ( Electromagnetic Fields) On the Bone Andmentioning

confidence: 99%

The effects of EMF (ELECTROMAGNETIC FIELDS) on the Bone and Cartilage Tissue

Sert¹

2017

J Nov Physiother Rehabil

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Environmental electromagnetic fi elds are nowadays available in all environments today. These areas affect the biological system. Controlled interactions with elecrtomagnetic fi elds can have positive effects when unrestricted interactions have negative effects. Uncontrolled exposure to low-frequency electromagnetic fi elds can cause adverse effects such as signal transduction in cells and tissues, cell membrane structure, ion channels, molecular interactions, DNA damage. But contrary to controlled exposure, it positively affects tissues. The most obvious example of this is seen in the bone and cartilaginous tissue. Repairing fractures and damage in bone and cartilage.

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Bioeffects of moderate-intensity static magnetic fields on cell cultures

Cited by 253 publications

References 156 publications

Magnetic Targeting of Human Peripheral Blood CD133⁺Cells for Skeletal Muscle Regeneration

Magnetic Targeting of Human Peripheral Blood CD133⁺Cells for Skeletal Muscle Regeneration

Magnetic Water Treatment in Environmental Management: A Review of the Recent Advances and Future Perspectives

The effects of EMF (ELECTROMAGNETIC FIELDS) on the Bone and Cartilage Tissue

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Bioeffects of moderate-intensity static magnetic fields on cell cultures

Cited by 253 publications

References 156 publications

Magnetic Targeting of Human Peripheral Blood CD133+Cells for Skeletal Muscle Regeneration

Magnetic Targeting of Human Peripheral Blood CD133+Cells for Skeletal Muscle Regeneration

Magnetic Water Treatment in Environmental Management: A Review of the Recent Advances and Future Perspectives

The effects of EMF (ELECTROMAGNETIC FIELDS) on the Bone and Cartilage Tissue

Contact Info

Product

Resources

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Magnetic Targeting of Human Peripheral Blood CD133⁺Cells for Skeletal Muscle Regeneration

Magnetic Targeting of Human Peripheral Blood CD133⁺Cells for Skeletal Muscle Regeneration