Biodynamics of copper oxide nanoparticles and copper ions in an oligochaete – Part I: Relative importance of water and sediment as exposure routes

Tools and rules for modelling uptake and bioaccumulation of nanomaterials in invertebrate organisms

“…73 Several studies have used PBPK or biodynamic models to quantify the bioaccumulation of different nanomaterials, with model formulations. 5,9,21,22,76 Studies on metal-based nanomaterials are generally based on the total metal content and do not take the different forms of the materials into account, although recent studies have focussed on this. 14 A modelling example on the uptake of different forms of Ag in earthworms illustrated the importance of form-specific approaches, and uptake levels and forms of Ag (as particulate or ionic uptake) were found to depend on i.e.…”

Nanomaterials in the aquatic environment: A European Union–United States perspective on the status of ecotoxicity testing, research priorities, and challenges ahead

“…Furthermore, most published papers seem biased toward pelagic organisms, with fewer studies on benthic organisms. Of the benthic studies, the freshwater oligochaete Lumbriculus variegatus and insect larva Chironomus riparius and the estuarine polychaetes Capitella teleta and Nereis diversicolor have been the focus of some sedimentary studies [6][7][8][9][10][11][12][13][14].…”

An assessment of the importance of exposure routes to the uptake and internal localisation of fluorescent nanoparticles in zebrafish (Danio rerio), using light sheet microscopy

“…In general, there is a lack of information on the extent of NP uptake at the organism level, and recent concern has been raised regarding the relationship between the uptake route and internal localisation of NPs both in vivo and in vitro (Bondarenko et al 2013;Fabrega et al 2011;Ma et al 2013;Menard et al 2011;Scown et al 2010;Tourinho et al 2012;Xin et al 2014). The influence of aqueous or dietary NP exposure has been examined in fish (Ates et al 2014;Skjolding et al 2014) and aquatic invertebrates (Croteau et al 2014;Larguinho et al 2014;Ramskov et al 2015;Dai et al 2015); however, knowledge regarding the link between exposure route and localisation is still somewhat limited (Croteau 2014;Ramskov et al 2015).…”