The purpose of this article is to analyze and describe sustainable practices based on biodiversity assets adopted by one of the largest global cosmetics company, located in Brazil. The company occupies the 19th position of the Global Ranking 100 Sustainability. The research method is bibliographic research that employed open, non-classified documents publicized by the company. The main findings of the study underscore the relevance of the rural communities in developing a supply chain based on biodiversity as well as the importance of the relationships among the tiers to implement a sustainable business model. The company relies on high-quality products associated with environmental development. Currently, biodiversity suppliers account for 80% circa of natural raw materials, the so-called biodiversity asset, which represents the core of the sustainable business model of the company. The findings can be generalized by helping other supply chains to develop and implement sustainable business models supported by biodiversity. Such type of a model can help companies achieve expressive business performance and, at the same time, social relevance to peripheral or vulnerable rural communities.