“…NIPAAm-based polymers exhibit a lower critical solution temperature (LCST) at ~32–33 °C in aqueous solution, which can be easily adjusted to physiological temperature through the modification of the hydrophilic/hydrophobic balance in the polymer with comonomers [ 6 , 7 , 8 , 9 , 10 ]. There are numerous applications of the sharp phase transition, which can be a reversible swelling change for crosslinked systems, especially in the designing of a controlled release system e.g., drug delivery, analytical separation and detection [ 11 , 12 , 13 , 14 , 15 ].…”