“…In literature, different HPLC methods have been developed and validated for the analysis of xenoestrogens in water. Among them, HPLC with electrochemical detection [10] , HPLC with fluorescence detection [ 11 , 12 ], and HPLC-DAD [13] , were applied for monitoring xenoestrogens during degradation processes in water [ 11 , 13 ]. However, it is worth noting that these methods employed the solid phase extraction (SPE) technique as a preconcentration step, with the drawback of increasing the costs and time of sample preparation for the analysis.…”