Biodegradable Tragacanth Gum Based Silver Nanocomposite Hydrogels and Their Antibacterial Evaluation

Rao, K. Madhusudhana; Kumar, Anuj; Rao, K.S.V. Krishna; Haider, Adnan; Han, Sung Soo

doi:10.1007/s10924-017-0989-2

Cited by 40 publications

(12 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The nanocomposites exhibited increased thermal stability compared to the hydrogel, with a degradation temperature of 235 °C for the composite and 227 °C for the gel. These findings are consistent with the results obtained by Rao et al [42]. They showed that Ag-loaded hydrogels had improved the thermal stability in comparison to the initial hydrogels.…”

Section: Resultssupporting

confidence: 93%

“…These results imply that the hydrogels act as an efficient template for the preparation of AgNPs [39,40]. The polymeric chains within the network provide stabilization and easy growth of AgNPs with minimal aggregation, the latter of which is known to reduce the antimicrobial properties [10,41,42]. These results were confirmed by FE-SEM and EDX analyses on the sample B which showed a dispersion and distribution of the particles in the polymeric network (Figure 7).…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Polyaspartamide Functionalized Catechol-Based Hydrogels Embedded with Silver Nanoparticles for Antimicrobial Properties

et al. 2018

View full text Add to dashboard Cite

In this study, polyaspartamide-based hydrogels were synthesized by boron-catechol coordination followed by incorporation of AgNPs into the materials. Free catechol moieties were exploited to produce AgNPs. TEM analyses displayed AgNPs of less than 20 nm in diameter and with minimum aggregation, attesting the role of hydrogels to act as an efficient template for the production of dispersed particles. XRD analyses confirmed the mean particle size using the Scherrer equation. Release kinetic studies were performed in DMEM medium, showing a slow release over a long time-period. Finally, the MIC and MBC were determined, demonstrating a bacteriostatic and bactericidal effect against Gram-positive S. aureus and Gram-negative E. coli.

show abstract

Section: Resultssupporting

confidence: 93%

Section: Resultsmentioning

confidence: 99%

Polyaspartamide Functionalized Catechol-Based Hydrogels Embedded with Silver Nanoparticles for Antimicrobial Properties

et al. 2018

View full text Add to dashboard Cite

show abstract

“…In addition, these wound products exhibited 98% cell viability of human fibroblast cells and showed good wound healing behavior by involving the significant rate of migration of the cells [199]. Silver NPs (AgNPs)-incorporated GT hydrogels showed excellent antibacterial behavior against E. coli (Gram-negative) and Bacillus subtilis (Gram-positive) [200]. Polyelectrolyte complex (PEC) hydrogels have shown great potential in the biomedical area [201,202], especially tissue engineering applications.…”

Section: Wound Dressingmentioning

confidence: 99%

Recent Advances in Natural Gum-Based Biomaterials for Tissue Engineering and Regenerative Medicine: A Review

et al. 2020

Self Cite

View full text Add to dashboard Cite

The engineering of tissues under a three-dimensional (3D) microenvironment is a great challenge and needs a suitable supporting biomaterial-based scaffold that may facilitate cell attachment, spreading, proliferation, migration, and differentiation for proper tissue regeneration or organ reconstruction. Polysaccharides as natural polymers promise great potential in the preparation of a three-dimensional artificial extracellular matrix (ECM) (i.e., hydrogel) via various processing methods and conditions. Natural polymers, especially gums, based upon hydrogel systems, provide similarities largely with the native ECM and excellent biological response. Here, we review the origin and physico-chemical characteristics of potentially used natural gums. In addition, various forms of scaffolds (e.g., nanofibrous, 3D printed-constructs) based on gums and their efficacy in 3D cell culture and various tissue regenerations such as bone, osteoarthritis and cartilage, skin/wound, retinal, neural, and other tissues are discussed. Finally, the advantages and limitations of natural gums are precisely described for future perspectives in tissue engineering and regenerative medicine in the concluding remarks.

show abstract

“…Presence of functional groups such as, carboxyl and hydroxyl facilitates the interaction of TG with different cross‐linking agents and monomers to form TG hydrogels . Being naturally abundant, non‐toxic, biocompatible and stable over a wide pH range, it has been applied for the fabrication of hydrogel‐based biomaterials for medical applications . Furthermore, TG holds approval by USA GRAS in 1961 for their application in food and pharmaceutical industries .…”

Section: Introductionmentioning

confidence: 99%

Tragacanth Hydrogel Integrated CeO₂@rGO Nanocomposite as Reusable Photocatalysts for Organic Dye Degradation

et al. 2020

View full text Add to dashboard Cite

Sunlight‐driven photocatalytic degradation has attracted great attention to tackle the issue of water contaminating organic dyes. As a proof of concept, we propose that nanoceria (CeO2) decorated on the surface of reduced graphene oxide (rGO), could effectively degrade pollutant organic dyes namely methylene blue (MB) and congo red (CR), when exposed to sunlight. The formation of as‐synthesized nanocomposite (CeO2@rGO) was monitored using UV‐visible, Fourier transfer infrared (FTIR) and RAMAN spectroscopy, X‐ray diffraction (XRD), Photoluminescence (PL), and Field emission scanning electronic microscopy (FESEM). Time‐dependent dye degradation was observed for up to 5 h and followed Langmuir‐Hinshelwood first‐order kinetics. Notably, at equivalent concentrations (2 mg), CeO2@rGO exhibited enhanced degradation of MB (∼92 %) and CR (∼83 %) dyes when compared to bare CeO2. The photocatalytic efficiency of CeO2@rGO was further enhanced by integrating in a polymer hydrogel fabricated using tragacanth (TG), a natural gum. The hydrogel photocatalyst (CeO2@rGO‐TG) exhibited ∼91 % MB degradation, at half the amount of CeO2@rGO in free form. More importantly, CeO2@rGO‐TG could be easily separated from the dye solution and re‐employed for multiple cycles of degradation.

show abstract

Biodegradable Tragacanth Gum Based Silver Nanocomposite Hydrogels and Their Antibacterial Evaluation

Cited by 40 publications

References 41 publications

Polyaspartamide Functionalized Catechol-Based Hydrogels Embedded with Silver Nanoparticles for Antimicrobial Properties

Polyaspartamide Functionalized Catechol-Based Hydrogels Embedded with Silver Nanoparticles for Antimicrobial Properties

Recent Advances in Natural Gum-Based Biomaterials for Tissue Engineering and Regenerative Medicine: A Review

Tragacanth Hydrogel Integrated CeO₂@rGO Nanocomposite as Reusable Photocatalysts for Organic Dye Degradation

Contact Info

Product

Resources

About

Biodegradable Tragacanth Gum Based Silver Nanocomposite Hydrogels and Their Antibacterial Evaluation

Cited by 40 publications

References 41 publications

Polyaspartamide Functionalized Catechol-Based Hydrogels Embedded with Silver Nanoparticles for Antimicrobial Properties

Polyaspartamide Functionalized Catechol-Based Hydrogels Embedded with Silver Nanoparticles for Antimicrobial Properties

Recent Advances in Natural Gum-Based Biomaterials for Tissue Engineering and Regenerative Medicine: A Review

Tragacanth Hydrogel Integrated CeO2@rGO Nanocomposite as Reusable Photocatalysts for Organic Dye Degradation

Contact Info

Product

Resources

About

Tragacanth Hydrogel Integrated CeO₂@rGO Nanocomposite as Reusable Photocatalysts for Organic Dye Degradation