Biodegradable Polyvinyl Alcohol Vascular Stents: Structural Model and Mechanical and Biological Property Evaluation

Lin, Mei‐Chen; Lou, Ching‐Wen; Lin, Jan‐Yi; Lin, Ting An; Chen, Yueh-Sheng; Lin, Jia‐Horng

doi:10.1016/j.msec.2018.05.030

Cited by 32 publications

(29 citation statements)

References 37 publications

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“…Polyvinyl alcohol (PVA) and polylactic acid (PLA) fibers are two stand-out representative biodegradable fibers which are widely used in the preparation of biodegradable bone scaffolds [21,22,23]. In this study, we evaluate the performance of HA coating prepared by electrodeposition on PVA/PLA braid.…”

Section: Introductionmentioning

confidence: 99%

Properties and Mechanism of Hydroxyapatite Coating Prepared by Electrodeposition on a Braid for Biodegradable Bone Scaffolds

Ling

Lin

et al. 2019

Nanomaterials

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Hydroxyapatite (HA) coating is successfully prepared by electrodeposition on the surface of polyvinyl alcohol (PVA)/polylactic acid (PLA) braid which serves as a potential biodegradable bone scaffold. The surface morphology, element composition, crystallinity and chemical bonds of HA coatings at various deposition times (60, 75, 90, 105 and 120 min) are characterized by scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDAX), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR), respectively. Average Surface roughness (Ra) of HA coating is observed by confocal microscopy. The results reveal that the typical characteristic peaks of the FTIR spectrum confirm that HA coating is successfully prepared on the rugged surface of the PVA/PLA braid. The XRD results indicate that the crystallinity of HA can be improved by increasing deposition time. In the 90 min-deposition, hydroxyapatite has a dense and uniform coating morphology, Ca/P ratio of 1.7, roughness of 0.725 μm, which shows the best electrodeposition performance. The formation mechanism of granular and plate-like hydroxyapatite crystals is explained by the structural characteristics of a hydroxyapatite unit cell. This study provides a foundation for a bone scaffold braided by biodegradable fibers.

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Section: Introductionmentioning

confidence: 99%

Properties and Mechanism of Hydroxyapatite Coating Prepared by Electrodeposition on a Braid for Biodegradable Bone Scaffolds

Ling

Lin

et al. 2019

Nanomaterials

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“…Chitosan solution serves as a crosslinking bridge. After the braids are dried at 40°C for 24 h, they are crosslinked with 1 wt% genipin solution for another 48 h, and dried again at 40°C for 24 h 22,23 . The crosslinking process with chitosan and genipin separately is considered 1 cycle, and PVA hollow braids need to processed with 3 cycles repeatedly.…”

Section: Methodsmentioning

confidence: 99%

Genipin‐crosslinking polyvinyl alcohol hollow braids degradable tissue engineering scaffolds: Manufacturing techniques and property evaluations

Jhang

Lin

Chen

2021

J of Applied Polymer Sci

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Tissue engineering has been developed with the aim of improving the regeneration and recovery of impaired tissues and organs. Biodegraded scaffolds serve the aforementioned functions and can also be decomposed by means of metabolism. They have no biological toxicity and save patients from injuries by the second surgery, which makes biodegradable scaffolds a new development trend in the tissue engineering. In this study, the textile engineering and chemical crosslinking techniques are employed to produce biodegradable polyvinyl alcohol (PVA) hollow braids, serving as the tissue engineering scaffolds. The process involves two types of products, including the twisted yarns and hollow braids. The twist number of PVA twisted yarns is changed to form different PVA twisted yarns, which are then used to braided into hollow braids via the braiding technology. Therefore, the hollow braids are basically composed three types of PVA twisted yarns. Next, the surface observation, mechanical properties, and degradation of the products are then evaluated. The test results indicate that PVA twisted yarns exhibit the optimal mechanical properties when being twisted with 3 turns/inch. Any higher twist counts result in over twist in the twisted yarns. The optimal hollow braids are composed of PVA twisted yarns with a twist counts being 3 turns/inch. Afterwards, hollow braids are crosslinking with genipin, thereby obtaining greater mechanical strength of 23.6 N and higher decomposition rate of 0.8. The specified hollow braids are suitable for the use as tissue engineering scaffolds.

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“…During the past few decades, the growth in the use of structural polymer composites has resulted in the need for better characterizations of the materials under working conditions. A strong driving force for new polymer composites is the fact that these materials can perform equally well as metals, especially under low‐temperature application nonferrous die castings have been used . In addition, polymer composites are highly noncorrosive, with the ability to be tailored and designed to any shape and size.…”

Section: Introductionmentioning

confidence: 99%

“…In addition, polymer composites are highly noncorrosive, with the ability to be tailored and designed to any shape and size. In the case of fiber glass‐polymer composites, the fiber choice, arrangement, and proportions are independently controlled by the fabricator . investigated the tensile behavior of polypropylene (PP) in the temperature range of 20 to 150 °C and have focused on the PP physical properties, morphology and microstructure .…”

Section: Introductionmentioning

confidence: 99%

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Effects of temperature and strain rate on the tensile behavior of polypropylene composites insulator coatings used in offshore deepwater pipelines

Vipulanandan

Guezo

2017

J of Applied Polymer Sci

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Polypropylene (PP) composites are being increasingly used as thermal insulation coatings in both onshore and offshore pipelines. In this study, the direct tensile behavior of pure PP, PP with glass microsphere filler, and PP with 65% glass filler were investigated at 22, 60, and 90 °C temperatures at various strain rates from 0.003/min to 0.300/min. Fourier transform infrared spectroscopy and scanning electron microscope studies were used to characterize the materials. Stress–strain relationships of the materials were nonlinear in the elastic and inelastic domains. Addition of glass fiber to the PP increased the elastic modulus, but the yield strength and yield strain were reduced along with the ductility. Based on the experimental results, constitutive models coupling the strain rate and temperature have been developed to predict the yield strength, the initial elastic modulus and secant modulus at yield for the PP composites. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45209.

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Biodegradable Polyvinyl Alcohol Vascular Stents: Structural Model and Mechanical and Biological Property Evaluation

Cited by 32 publications

References 37 publications

Properties and Mechanism of Hydroxyapatite Coating Prepared by Electrodeposition on a Braid for Biodegradable Bone Scaffolds

Properties and Mechanism of Hydroxyapatite Coating Prepared by Electrodeposition on a Braid for Biodegradable Bone Scaffolds

Genipin‐crosslinking polyvinyl alcohol hollow braids degradable tissue engineering scaffolds: Manufacturing techniques and property evaluations

Effects of temperature and strain rate on the tensile behavior of polypropylene composites insulator coatings used in offshore deepwater pipelines

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