Biodegradable polymeric coatings for surface modification of magnesium-based biomaterials

Kannan, M. Bobby

doi:10.1016/b978-1-78242-078-1.00013-x

Cited by 11 publications

(6 citation statements)

References 64 publications

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“…The interfacial interaction between the hydrophilic polymer layer and the iron surface generates the increasing degradation of iron. The degradation begins by the oxidative degradation of the PEG coating layer followed by the formation of defects in the polymer layer because the hydrophilic polymers undergo bulk degradation [87]. The defects allow the penetration of a solution into the iron substrate.…”

Section: Discussionmentioning

confidence: 99%

An In Vitro Corrosion Study of Open Cell Iron Structures with PEG Coating for Bone Replacement Applications

Haverová

Oriňáková

Oriňák

et al. 2018

Metals

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Abstract:Iron-based substrates with polyethylene glycol coating were prepared as possible materials for biodegradable orthopedic implants. Biodegradable materials that provide mechanical support of the diseased tissue at the time of implanting and then disappear gradually during the healing process are sometimes favored instead of permanent implants. The implant degradation rate should match the time of the tissue regrowth. In this work, the degradation behavior of iron-based foams was studied electrochemically during immersion tests in Hanks' solution. The corrosion rate of the polyethylene glycol-coated samples increased and the corrosion potential shifted to more negative values. This indicates an enhanced degradation rate as compared to the uncoated material, fulfilling the goal of being able to tune the degradation rate. It is the interfacial interaction between the hydrophilic polymer layer and the iron surface that is responsible for the enhanced oxidation rate of iron.

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Section: Discussionmentioning

confidence: 99%

An In Vitro Corrosion Study of Open Cell Iron Structures with PEG Coating for Bone Replacement Applications

Haverová

Oriňáková

Oriňák

et al. 2018

Metals

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“…According to Kannan, a simple coating of a degradable polymer alone does not usually exhibit long‐term effectiveness in terms of controlling the corrosion of magnesium and magnesium alloys. Instead, hybrid coatings combining a ceramic component and a biodegradable polymer in the form of composite coatings should lead to better results.…”

Section: Discussion and Final Remarksmentioning

confidence: 99%

Tackling Mg alloy corrosion by natural polymer coatings—A review

Heise

Virtanen

Boccaccını

2016

J Biomedical Materials Res

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The field of protective coatings for magnesium and its alloys (e.g., AZ31) using natural polymers is reviewed. Polymers utilized are broadly divided into polysaccharides and proteins. For both polymer classes examples are given focusing on coating processing and characterization. Several analysing methods reported in literature are summarized highlighting the different characterization approaches applied in different studies, which makes difficult a direct comparison of the outcomes. In most cases, the protective behavior of coatings was determined using electrochemical impedance spectroscopy or by assessing hydrogen evolution in different fluids. Mechanical tests and in vitro cell culture studies have been also carried out on selected coating systems. Overall, the results show the possibility of applying protective coatings based on natural polymers on magnesium and its alloys, however, in vivo investigations are scarce so that long-term results in relevant conditions are not yet available. A comparison with the use of synthetic polymers is presented and current challenges and areas for future research are discussed, highlighting the need for further investigations in the field, which should enable broadening the applications of Mg and Mg alloys in medicine. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 2628-2641, 2016.

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“…[83,84] Various coating techniques have been employed to create functional polymeric layers on Mg alloys, including PEO, anodization, hydrothermal coating, MAO, chemical CCs, PVD, radiofrequency magnetron sputtering, and others. [85,86] Examples of polymeric coatings include biodegradable polymer-based coatings, biofunctionalized anticorrosive silane coatings, and self-assembled coatings. Specific biopolymers used for coatings include polyvinylidene fluoride, chitosan, alginate, cellulose, hyaluronic acid, cellulose acetate, chitin, and heparin.…”

Section: Polymeric Coatingsmentioning

confidence: 99%

Multifunctional Coatings on Mg‐Based Metallic Biomaterials and Implants

Li,

Kong,

Zhang

2024

Adv Eng Mater

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Multifunctional materials are propitious materials with numerous functionalities that make them an ideal option for implants and biomedical applications that should simultaneously fulfill various requirements, including satisfactory mechanical strength, biocompatibility, antibacterial property, hydrophilicity, drug delivery, etc. Magnesium, as a metallic biomaterial, fulfills the required mechanical properties, but unfortunately, in some ways alone, it cannot provide the required biological properties. For instance, Mg alloys suffer from poor corrosion resistance and high biodegradability, which should be carefully controlled. On the other hand, multifunctional materials alone are not able to provide the required properties in biomedical applications because the vast majority of them do not have the necessary strength and stability. Therefore, the use of magnesium together with multifunctional or composite coatings will be a very advantageous choice for meeting the needs of implants and biomedical materials. The current study focuses on the introduction and utilization of various multifunctional coatings and composites on Mg‐based alloys for biomedical applications. Numerous organic and inorganic materials could be utilized as composites or multifunctional materials, such as polymers, hydroxyapatites, hydrogels, calcium phosphates, alginates, hyaluronic acids, chitosan, etc. In this regard, numerous types of coating and composite materials, their production technologies, mechanisms, resultant properties, and the involved parameters are thoroughly discussed to provide a comprehensive guide for those interested in this field. It is hoped that this study will pave the way for the production of advanced and smart multifunctional materials with unique properties and play a role in the design of a new generation of Mg‐based biomedical materials.This article is protected by copyright. All rights reserved.

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Biodegradable polymeric coatings for surface modification of magnesium-based biomaterials

Cited by 11 publications

References 64 publications

An In Vitro Corrosion Study of Open Cell Iron Structures with PEG Coating for Bone Replacement Applications

An In Vitro Corrosion Study of Open Cell Iron Structures with PEG Coating for Bone Replacement Applications

Tackling Mg alloy corrosion by natural polymer coatings—A review

Multifunctional Coatings on Mg‐Based Metallic Biomaterials and Implants

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