Biodegradable photo-crosslinked poly(ether-ester) networks for lubricious coatings

Synthesis and characterization of novel degradable photocrosslinked poly(ether-anhydride) networks

“…The degradation rates of these crosslinked polymers were higher than those of the crosslinked polymers containing ester bonds based on polyether-co-poly(␣-hydroxy acid) diacrylate, 7,14 suggesting that only one anhydride bond at each end per macromer is more hydrolytically labile than several ester bonds per macromer. For comparison, crosslinked polymer networks based on PEG diacrylate, which contains only one ester bond at each end per macromer, did not degrade for over 1 year.…”

“…However, we can compare the contact angles of the crosslinked polymer network films of the diacrylated copolymers of polyether (PEG or PTMG) and 5 mol of lactide. 14 The contact angle of the PEG-based network with PEG molecular weight of 400 was 43.5 degree, while that of PTMG-based network with PTMG molecular weight of 2900 was 69.0 degree, suggesting that the PTMG-based samples were more hydrophobic than the PEG-based samples.…”

Controlled Release of Model Drug from Biodegradable Segmented Polyurethane Ureas: Morphological and Structural Features

“…Because the expedited degradation studies of biomaterials in basic solutions were previously reported and correlated to other in vitro methods. [17] The total time taken to degrade 3 different types of polymers such as PCL(530)(50)BDA, PCL(1250)(70)BDA and PCL(2000)(80)BDA was 3, 20 and 96 h respectively. The degradation of SPUU films is a function of molecular Table 3.…”

Electrostatic Assembly of Poly(ethylene glycol) Nanotubes

“…The tendency for PEG-based materials to swell and eventually dissolve [26,27] in water and other solvents potentially limits their use in applications where long-term stability is desired. Many routes to stabilizing PEG or to controlling the dissolution of PEG have been established: UV-crosslinked networks and hydrogels of PEG-derivatives [28][29][30] amphiphilic block copolymers, [31] covalent bonding to polyethylene terephthalte (PET), [32] and surface-grafting of oligoethylene oxides to gold. [33] In many of these studies, the resulting PEG-based materials were substrate-specific, control over surface topology was limited, and nanotubular structures-which are interesting for micro-and nanodevice fabrication and small-scale drug delivery vehicles-were not realized.…”