Biodegradable Behaviors of Ultrafine-Grained ZE41A Magnesium Alloy in DMEM Solution

Jiang, Jinghua; Zhang, Fan; Ma, Aibin; Song, Dandan; Liu, Huan; Qiang, Mingshan

doi:10.3390/met6010003

Cited by 16 publications

(5 citation statements)

References 22 publications

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“…The microstructure produced by MAD processing is more favorable: it is fine grained (~1 µm) and contains more corrosion-resistant particles of the Mg 41 Nd 5 phase, evenly distributed in the matrix. As reported in the literature, the formation of a uniform UFG structure can improve the corrosion resistance of magnesium alloys [25][26][27][28]. In our case, the uniformity of the distribution of the Mg 41 Nd 5 particles did not cause the occurrence of inhomogeneity of corrosion, suggesting that the formation of cathode-anode pairs with the metal matrix was not an issue here [29,30].…”

Section: Discussionsupporting

confidence: 76%

Modification of Biocorrosion and Cellular Response of Magnesium Alloy WE43 by Multiaxial Deformation

Anisimova

Martynenko

Новрузов

et al. 2022

Metals

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The study shows that multiaxial deformation (MAD) treatment leads to grain refinement in magnesium alloy WE43. Compared to the initial state, the MAD-processed alloy exhibited smoother biocorrosion dynamics in a fetal bovine serum and in a complete cell growth medium. Examination by microCT demonstrated retardation of the decline in the alloy volume and the Hounsfield unit values. An attendant reduction in the rate of accumulation of the biodegradation products in the immersion medium, a less pronounced alkalization, and inhibited sedimentation of biodegradation products on the surface of the alloy were observed after MAD. These effects were accompanied with an increase in the osteogenic mesenchymal stromal cell viability on the alloy surface and in a medium containing their extracts. It is expected that the more orderly dynamics of biodegradation of the WE43 alloy after MAD and the stimulation of cell colonization will effectively promote stable osteosynthesis, making repeat implant extraction surgeries unnecessary.

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Section: Discussionsupporting

confidence: 76%

Modification of Biocorrosion and Cellular Response of Magnesium Alloy WE43 by Multiaxial Deformation

Anisimova

Martynenko

Новрузов

et al. 2022

Metals

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“…Low stacking fault energy implies a wide separation of dislocations to cross-slipping. This difficulty interprets the relatively lower recovery rates, which results in lower erosion rates [41][42][43]. Figure 7 shows the variation of weight loss with ECAP passes as a function of slurry velocity.…”

Section: Effect Of Ecap On Erosion-corrosion At Different Test Durationsmentioning

confidence: 99%

“…At low velocities, the erodent is not completely suspended in the fluid; therefore, the erosion is unable to occur. It is recognized that erosion is a function of the fluid velocity (v) and it and be calculated by the nonlinear formula: Erosion = K·(v) n , where K is a constant depends upon particle size and impacting angle, and n is the velocity exponent [41,42]. Comparing the weight losses for pass zero (annealed copper) and four pass ECAP at different velocities it is observed that E-C resistances increased by 0%, 14%, 31.8%, and 13% at 1.4 m/s, 2.7 m/s, 3.8 m/s, and 5.4 m/s, respectively.…”

Section: Effect Of Ecap On Erosion-corrosion At Different Test Durationsmentioning

confidence: 99%

Effect of Equal Channel Angular Pressing (ECAP) on Erosion-Corrosion of Pure Copper

et al. 2017

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Abstract:During the past few decades, ultrafine-grained materials (UFG) have experienced rapid development. Enhanced mechanical and surface properties, such as strength, ductility and erosioncorrosion (E-C) resistance by refining the grain to ultra-fine/nanometer size has been achieved. The equal channel angular pressing (ECAP) is a popular severe plastic deformation (SPD) method to fabricate UFG bulk materials. In this research, the E-C behavior of commercial annealed pure copper subject to four passes of ECAP have been investigated. Hardness measurement of the copper specimen after four passes of ECAP showed an increase of 200% on the hardness value as compared with annealed condition. Simulated seawater was used as an E-C medium. The effect of different E-C parameters such as time, slurry flow velocity, impact angle, and solid particle concentration on ECAP process is studied. The results showed that ECAP enhances the E-C resistance of copper, and this behavior improves with increasing the pass number. Generally, a 30% rise in resistance to E-C was achieved after four ECAP passes as compared to coarse grain copper for the parameters studied in this work. Optical microscopy was used to examine the microstructure and material removal mechanism of the annealed copper. Scanning electron microscopy (SEM) was used to validate the reduction of grain size due to ECAP process. Furthermore, examination of the surface roughness of the copper at different ECAP passes showed that for the same E-C condition the increment of ECAP passes leads to a smoother surface.

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“… Corrosion rate reported in samples of magnesium processed via ECAP [ 52 , 55 , 56 , 57 , 58 , 59 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 69 , 71 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 82 , 83 , 84 , 85 , 86 , 87 ] and HPT [ 19 , 88 , 90 , 91 , 92 , 93 , 94 , 95 , 97 , 98 , 99 , 100 ] plotted as a function of the grain size. …”

Section: Figurementioning

confidence: 99%

An Overview on the Effect of Severe Plastic Deformation on the Performance of Magnesium for Biomedical Applications

et al. 2023

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There has been a great interest in evaluating the potential of severe plastic deformation (SPD) to improve the performance of magnesium for biological applications. However, different properties and trends, including some contradictions, have been reported. The present study critically reviews the structural features, mechanical properties, corrosion behavior and biological response of magnesium and its alloys processed by SPD, with an emphasis on equal-channel angular pressing (ECAP) and high-pressure torsion (HPT). The unique mechanism of grain refinement in magnesium processed via ECAP causes a large scatter in the final structure, and these microstructural differences can affect the properties and produce difficulties in establishing trends. However, the recent advances in ECAP processing and the increased availability of data from samples produced via HPT clarify that grain refinement can indeed improve the mechanical properties and corrosion resistance without compromising the biological response. It is shown that processing via SPD has great potential for improving the performance of magnesium for biological applications.

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Biodegradable Behaviors of Ultrafine-Grained ZE41A Magnesium Alloy in DMEM Solution

Cited by 16 publications

References 22 publications

Modification of Biocorrosion and Cellular Response of Magnesium Alloy WE43 by Multiaxial Deformation

Modification of Biocorrosion and Cellular Response of Magnesium Alloy WE43 by Multiaxial Deformation

Effect of Equal Channel Angular Pressing (ECAP) on Erosion-Corrosion of Pure Copper

An Overview on the Effect of Severe Plastic Deformation on the Performance of Magnesium for Biomedical Applications

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