Bioconcentration and Behavioral Interference Effect of Diazepam on Adult Japanese Medaka (Oryzias latipes)
Sijing WANG,
Mengcheng ZHUO,
Kun CHEN
et al.
Abstract:As one of the most commonly detected polluting drugs in the environment, diazepam (DZP) has been widely detected in rivers, soil, and organisms. To better understand the bioconcentration of DZP in fish and its impact on fish behaviors, we exposed both female and male medaka to a DZP (120 µg/L) for 7 days, and then transformed them to clean dechlorinated water for 3 days of depuration. Regardless of gender, DZP can rapidly accumulate in the brain and liver tissue and reach a stable phase within 24 hours of expo… Show more
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