Bioconcentration and Antioxidant Status Responses in Zebrafish (Danio Rerio) Under Atrazine Exposure

Abstract

Abstract-The present study was planned designed to investigate the chronic impacts of herbicide atrazine exposure on stress biomarkers acetylcholinesterase activity (AChE) and oxidative stress responses in brain of zebrafish (Danio rerio), and determine the bioconcentration of atrazine in whole body of fish. Chronic exposure to atrazine unveiled a markedly discourage in the activity of AChE. However, significant increase in the activities of catalase (CAT) and superoxide dismutase (SOD) and both influenced by atraizine, and CAT was over sensitivity to atrazine compared with SOD. The highest bioconcentration factor (BCF) of atrazine in the fish treated was (12.8543×10 4 and 13.5891×10 4 ) after 24h exposure to (0.957 and 1.913 mg L -1 ) and 13.238×10 4 , after 25 d exposure to 0.638 mg L −1 of atrazine respectively. This study showed that the zebrafish have ability to bioaccumulate of the herbicide atrazine rapidly. atrazine accumulation in zebrafish has a private importance due to the implication of atrazine in chronically health problems, as well as the information contained in our study is useful for understand the mechanism of atrazine induced oxidative stress in fish.

Sub-chronic Effects of Zinc oxide Nanoparticles on Ovary, Gills, Kidney and Liver of Fresh Water Fish (Cyprinus carpio): histopathological Study

“…The fish were exposed to three concentrations of ZnO nanoparticles which computed using 1/15 th , and 1/7 th of the 96 LC50 value which determined in this study [20] which were = 250 mg / L and 500 mg / L correspondingly.…”

Environmentally Relevant Atrazine Exposure Leads to Increases in DNA Damage and Changes in Morphology in the Hepatopancreas of Crayfish (Faxonius Virilis)

“…Gunkel and Streit (1980) suggest that ATR enters the body of most aquatic organisms via the gills and can be concentrated in various organs and tissues. ATR has been shown to accumulate in the liver/hepatopancreas, gallbladder and ovaries in sh (Danio rerio, Tilapia sparrmanii, Coregonus fera, Cyprinus carpio) and in the visceral mass, foot and mantle of bivalves (Ancylus uviatilis, Anodontites trapesialis and Corbicula uminea) following an acute exposure (Gunkel and Streit, 1980;du Preez and Van Vuren, 1992;Jacomini et al, 2006;Xing et al, 2012;Al-Sawa and Yan, 2013). ATR was also shown to cause DNA damage in cells of tissues where it is known to accumulate.…”

Environmentally relevant atrazine exposure leads to increases in DNA damage and changes in morphology in the hepatopancreas of crayfish (Faxonius virilis)

“… Gunkel and Streit (1980) suggest that atrazine enters the body of most aquatic organisms via the gills and can be concentrated in various organs and tissues. Atrazine has been shown to accumulate in the liver/hepatopancreas, gallbladder and ovaries in fish ( Danio rerio, Tilapia sparrmanii, Coregonus fera, Cyprinus carpio ) and in the visceral mass, foot and mantle of bivalves ( Ancylus fluviatilis, Anodontites trapesialis and Corbicula fluminea ) following an acute exposure ( Gunkel and Streit, 1980 ; du Preez and Van Vuren, 1992 ; Jacomini et al, 2006 ; Xing et al, 2012 ; Al-Sawafi and Yan, 2013 ). Atrazine was also shown to cause DNA damage in cells of tissues where it is known to accumulate.…”