Biocompatible, stretchable and mineral PVA–gelatin–nHAP hydrogel for highly sensitive pressure sensors

Zhu, Yi; Lu, Weipeng; Guo, Yanchuan; Chen, Yu; Wu, You; Lu, Haojun

doi:10.1039/c8ra06193a

Cited by 34 publications

(14 citation statements)

References 42 publications

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“…A newly developed waterproof device without a tubular structure was considered able to measure the pressure in the vitreous gel without clogging and was used to monitor the IOP in the vitreous cavity to address the viscosity of the vitreous body. A method to measure the pressure applied to a gel via a strain change has been reported previously 7 . To clarify the accuracy of the device, we modified the method partially and performed a control experiment to evaluate how accurately the device measures the pressure in a gel by enclosing it in an artificial gel and measuring the water pressure.…”

Section: Investigation Of Intraocular Pressure Of the Anterior Chambementioning

confidence: 99%

Investigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method

Nagae

Sawamura

Aihara

2020

Sci Rep

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To evaluate a new method of measuring the intraocular pressure (IOP) in the vitreous cavity. IOPs in the anterior chamber and vitreous cavities of 24 porcine eyes (12 eyes with lenses and 12 eyes without lenses) were measured directly, continuously, and simultaneously. We used a needle as a part of the pressure sensor to measure the anterior chamber IOP and a disk-shaped sensor to measure the vitreous cavity IOP. A significant group-by-condition interaction on the vitreous cavity IOP between the two groups (phakia and aphakia) and four conditions of anterior chamber IOP were observed (F[3,258] = 5.8564, p < 0.001). A positive correlation was observed between the vitreous cavity IOP and anterior chamber IOP in both the phakia group (R = 0.96, p < 0.001) and the aphakia group (R = 0.97, p < 0.001). No significant correlation was observed between the ΔIOPv-a (vitreous cavity IOP − anterior chamber IOP) and anterior chamber IOP in either group (phakia group: R = − 0.18, p = 0.034; aphakia group: R = − 0.029, p = 0.73). The vitreous cavity IOP measured with the new sensor was well-correlated with the anterior chamber IOP in the physiological range tested.

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Section: Investigation Of Intraocular Pressure Of the Anterior Chambementioning

confidence: 99%

Investigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method

Nagae

Sawamura

Aihara

2020

Sci Rep

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“…Dong et al [18] demonstrated a wearable piezoresistive pressure sensor with pressure sensitivity of 0.05 kPa −1 using a PVA-PAAm hydrogel. Besides, various other hydrogels, such as PAAm composite hydrogels, [19] alginate composite hydrogels, [20] gelatin hydrogels, [21] and Fmoc-FF-PAni composite hydrogels, [22] were also synthesized to construct wearable pressure sensors. These studies demonstrated the feasibility of using hydrogels in developing wearable pressure sensors.…”

Section: Introductionmentioning

confidence: 99%

Gelatin Methacryloyl‐Based Tactile Sensors for Medical Wearables

Zhang

Chen

et al. 2020

Adv Funct Materials

119

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Gelatin methacryloyl (GelMA) is a widely used hydrogel with skin-derived gelatin acting as the main constituent. However, GelMA has not been used in the development of wearable biosensors, which are emerging devices that enable personalized healthcare monitoring. This work highlights the potential of GelMA for wearable biosensing applications by demonstrating a fully solution-processable and transparent capacitive tactile sensor with microstructured GelMA as the core dielectric layer. A robust chemical bonding and a reliable encapsulation approach are introduced to overcome detachment and water-evaporation issues in hydrogel biosensors. The resultant GelMA tactile sensor shows a highpressure sensitivity of 0.19 kPa −1 and one order of magnitude lower limit of detection (0.1 Pa) compared to previous hydrogel pressure sensors owing to its excellent mechanical and electrical properties (dielectric constant). Furthermore, it shows durability up to 3000 test cycles because of tough chemical bonding, and long-term stability of 3 days due to the inclusion of an encapsulation layer, which prevents water evaporation (80% water content). Successful monitoring of various human physiological and motion signals demonstrates the potential of these GelMA tactile sensors for wearable biosensing applications.

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“…Gelatin has been used for many years in the food, pharmaceutical, and cosmetic industries, and has been an ideal material in bone, cartilage, and vascular tissue engineering in the last decade, with its high biocompatibility. For this reason, it has been preferred in many flexible electronic applications such as sensors, [249] electrodes, [250] wearable electronics, [251] and electronic skin, [171] especially with in-body integration.…”

Section: Gelatinmentioning

confidence: 99%

Sustainable Macromolecular Materials in Flexible Electronics

Kılıçarslan

Bozyel

Gökcen

et al. 2022

Macro Materials & Eng

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With advances in electronics, the concept of flexible electronics has left traditional designs behind. Many concepts, such as sensors, transistors, soft robotics, data, and energy storage devices have begun to find more widespread and flexible areas of use. From this point of view, using environmentally friendly, abundant, and renewable natural materials that reduce carbon emissions in the production and disposal of these components is the first step toward the concept of sustainable flexible electronics. This review deals with the integration of sustainable natural materials obtained from plant, animal, and bacterial sources into sensors, displays, data storage, power generation, and soft robotic systems, with appropriate examples compiled from the last ten years. In addition, limitations in the use of sustainable materials as flexible electronic components and their potential for use in innovative electronic applications in the future are foreseen.

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Biocompatible, stretchable and mineral PVA–gelatin–nHAP hydrogel for highly sensitive pressure sensors

Abstract: A biocompatible, stretchable and mineral conductive hydrogel used for highly sensitive pressure sensors.

Cited by 34 publications

References 42 publications

Investigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method

Investigation of intraocular pressure of the anterior chamber and vitreous cavity of porcine eyes via a novel method

Gelatin Methacryloyl‐Based Tactile Sensors for Medical Wearables

Sustainable Macromolecular Materials in Flexible Electronics

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