Biocompatible hydrogels based on chitosan, cellulose/starch, PVA and PEDOT:PSS with high flexibility and high mechanical strength

Dodda, Jagan Mohan; Azar, Mina Ghafouri; Bělský, Petr; Šlouf, Miroslav; Brož, Antonín; Bačáková, Lucie; Kadlec, J.; Remiš, Tomáš

doi:10.1007/s10570-022-04686-4

Cited by 20 publications

(11 citation statements)

References 71 publications

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“…Tough and strong cellulose hydrogels. (a) and (b) Photographs of the stretching process of the tough cellulose hydrogel, (c) and (d) mechanical properties of cellulose hydrogels made by using cellulose nanofibers/EmimAc with different solid contents, (e) and (f) photographs of the cellulose hydrogel made by using cellulose nanofibers/EmimAc with a solid content of 25%, and (g) toughness comparison with polysaccharide-based hydrogels in previous studies. ,− …”

Section: Resultsmentioning

confidence: 98%

Tough and Strong All-Biomass Plastics from Agricultural and Forest Wastes via Constructing an Aggregate of Hydrogen-Bonding Networks

Xia

et al. 2023

ACS Sustainable Chem. Eng.

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The development of all-biomass materials to replace conventional plastics has been gradually becoming a focus. However, all-biomass plastics, especially those fabricated from agricultural and forestry wastes, have the obstacles of poor formability and/or low toughness. Herein, we demonstrated a facile, efficient, and easy-to-scale method to significantly improve the formability and toughness of biomass materials via constructing an aggregate of hydrogen-bonding networks, where the relatively weak hydrogen bonding could be sacrificed during stretching. After a continuous preparation process that combined a paper-making process with an in situ welding process, the regenerated cellulose material with a layered microstructure was spontaneously formed. The interlayer hydrogen-bonding interactions could dissipate energy during stretching. As a result, the cellulose plastics were tough and strong. The tensile strength, strain, and toughness reached 154.9 MPa, 57.7%, and 81.76 MJ/m3, respectively, which were markedly higher than those of previous cellulose-based materials. The corresponding cellulose hydrogel exhibited an excellent strength of 9.5 MPa and a high strain of 171.4% also. During this scalable process, a 1-ethyl-3-methylimidazolium acetate (EmimAc) aqueous solution worked as a dispersant and a solvent, and a high solid content of cellulose/EmimAc (20 wt %) was used. Based on such an effective method, various agricultural and forestry wastes, including corn straw, wheat straw, grass, and wood powder, could be directly processed into high-tough all-biomass films, indicating a huge potential in ecofriendly materials, environmental protection, and bioresource utilization.

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Section: Resultsmentioning

confidence: 98%

Tough and Strong All-Biomass Plastics from Agricultural and Forest Wastes via Constructing an Aggregate of Hydrogen-Bonding Networks

Xia

et al. 2023

ACS Sustainable Chem. Eng.

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“…dipole interactions) can also be incorporated in the polymeric network to ameliorate the identities of the flexible substrates. [58][59][60][61][62][63][64] The hydrogel networks formed by hydrogen bonds possess outstanding high toughness, extremotolerant property, and self-healing capability. For example, an injectable hydrogel with hydrogen bonds was fabricated using a mixture of hydrazide-modified poly(N-isopropylacrylamide-coacrylic acid) ( poly(NIPAM-co-AA)-hdz), aldehyde-functionalized dextrin, and poly(N-acryloyl glycinamide) (PNAGA).…”

Section: Nanoscale Reviewmentioning

confidence: 99%

Evolution of nanostructured skin patches towards multifunctional wearable platforms for biomedical applications

DODDA

Rybak

et al. 2023

Nanoscale

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“…The strongest peak was found at around 1425 cm −1 due to symmetric C α � C β (−O) stretching vibration, while peaks at around 1255, 1367, 1495, and 1533 cm −1 may correspond to C α �C α inter-ring stretching, C β −C β stretching, and symmetric and asymmetric stretching vibration of C α �C β (−H), respectively. 29,46,47 As the semi-cross-linked PSS/PVA hydrogel leads to a 3D polymer network and provides an abundance of hydrogen bonds, the intensity of the characteristic bands for the PEDOT was more intense compared with the pure PEDOT/PSS. Additionally, the shape of the peak that matched the symmetric stretching vibration of the C α �C β was sharper, and the peak width at half-height was narrower, which may be attributed to the interaction between the PSS/PVA and the PEDOT chain.…”

Section: Fabrication Of Icpn Filmsmentioning

confidence: 99%

Conducting Polymer-Hydrogel Interpenetrating Networks for Improving the Electrode–Neural Interface

Yan,

Wang,

et al. 2023

ACS Appl. Mater. Interfaces

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Implantable neural microelectrodes are recognized as a bridge for information exchange between inner organisms and outer devices. Combined with novel modulation technologies such as optogenetics, it offers a highly precise methodology for the dissection of brain functions. However, achieving chronically effective and stable microelectrodes to explore the electrophysiological characteristics of specific neurons in free-behaving animals continually poses great challenges. To resolve this, poly(3,4-ethylenedioxythiophene)/poly(styrenesulfonate)/poly(vinyl alcohol) (PEDOT/PSS/PVA) interpenetrating conducting polymer networks (ICPN) are fabricated via a hydrogel scaffold precoating and electrochemical polymerization process to improve the performance of neural microelectrodes. The ICPN films exhibit robust interfacial adhesion, a significantly lower electrochemical impedance, superior mechanical properties, and improved electrochemical stability compared to the pure poly(3,4-ethylenedioxythiophene)/poly(styrenesulfonate)(PEDOT/PSS) films, which may be attributed to the three-dimensional (3D) porous microstructure of the ICPN. Hippocampal neurons and rat pheochromocytoma cells (PC12 cells) adhesion on ICPN and neurite outgrowth are observed, indicating enhanced biocompatibility. Furthermore, alleviated tissue response at the electrode–neural tissue interface and improved recording signal quality are confirmed by histological and electrophysiological studies, respectively. Owing to these merits, optogenetic modulations and electrophysiological recordings are performed in vivo, and an anxiolytic effect of hippocampal glutamatergic neurons on behavior is shown. This study demonstrates the effectiveness and advantages of ICPN-modified neural implants for in vivo applications.

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Biocompatible hydrogels based on chitosan, cellulose/starch, PVA and PEDOT:PSS with high flexibility and high mechanical strength

Cited by 20 publications

References 71 publications

Tough and Strong All-Biomass Plastics from Agricultural and Forest Wastes via Constructing an Aggregate of Hydrogen-Bonding Networks

Tough and Strong All-Biomass Plastics from Agricultural and Forest Wastes via Constructing an Aggregate of Hydrogen-Bonding Networks

Evolution of nanostructured skin patches towards multifunctional wearable platforms for biomedical applications

Conducting Polymer-Hydrogel Interpenetrating Networks for Improving the Electrode–Neural Interface

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