Biocompatible fluorescent core–shell nanoparticles for ratiometric oxygen sensing

Tuning oxygen sensitivity of ruthenium complex exploiting silver nanoparticles

“…The calibration plots were nonlinear within the measured oxygen concentrations [15]. Not only the ruthenium based dyes but also other transition metal complexes and porphyrin derivatives developed to date exhibit nonlinear calibration data or Stern-Volmer plots especially for the large working ranges [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][20][21][22][23][24][25]. This is due to the uncontrollable high sensitivity of the exploited dyes towards oxygen.…”

“…On the other hand, recently, fabrication of mesoporous, micro and nano-scale matrix materials and their usage for gas sensing purposes have been studied [2,6,7,9,[13][14][15][16][17][20][21][22][23][24][25] structure with enhanced surface area, the feasibility of modification and reliable entrapment of fluorescent dyes within the cavities make them useful as solid matrix materials for the design of optical chemical sensors [25]. Besides, the development of micro and nanomaterials will support the design of new sensors, which represent enhanced analytical characteristics such as small size, robustness, low limit of detection values and enhanced relative signal change.…”

Soft fluorescent nanomaterials for biological and biomedical imaging

“…98, 99 In this method (Fig. 2), a hydrophobic polymer (PS) and a alkoxy silane (DTS) were coprecipitated with selected fluorophores into a basic water containing positively charged poly-L-lysine (PLL).…”

Iridium-Based Dual-Functional Nanoparticles for Far-Red Imaging and Photodynamic Therapy

“…It needs to point out that the PS-DTS hybrid matrix of Ir-NPs is highly oxygenpermeable, and other phosphorescent metal complexes (e.g. PdOEP and PtTFPP) have been doped into the same particle matrix to prepare highly sensitive oxygen nanosensors [29,31]. The mechanism of insensitivity of Ir-NPs against oxygen is not clear presently, and further work is needed.…”

“…In this work, a far-red phosphorescent hydrophobic iridium complex with emission wavelength at 668 nm was embedded into biocompatible NPs using a modified encapsulation-reprecipitation method [3,[29][30][31]. Phosphorescence of the complex was highly oxygen-sensitive in organic solvent, but became nearly independent of oxygen after being immobilized into particle matrix that was actually oxygen-permeable.…”