Biocompatibility of sol-gel hydroxyapatite-titania composite and bilayer coatings

Sidane, Djahida; Rammal, Hassan; Beljebbar, A.; Gangloff, Sophie C.; Chicot, Didier; Velard, Frédéric; Khireddine, Hafit; Montagne, Alex; Kerdjoudj, Halima

doi:10.1016/j.msec.2016.11.129

Cited by 65 publications

(41 citation statements)

References 52 publications

(56 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…From the 1980s until nowadays, a huge development in the sol-gel process was achieved. The research conducted allowed them to obtain OIH materials with applications in a wide range of areas, such as chemical and biosensors [13,85,86], in several transduction modes, from electrochemical [87][88][89][90][91] to optical [13,[92][93][94][95]; biomaterials for drug delivery [24,[96][97][98][99][100]; materials for improving bioactivity and biocompatibility of metallic substrates [101][102][103][104][105][106][107][108]; electronics [14]; environment [109][110][111]; optics [13,112,113]; medicine [53,[114][115][116][117]; functional smart coatings [31,38,73,118]; fuel and solar cells [119][120][121]…”

Section: Sol-gel Process: a Historical Perspective And Applicationsmentioning

confidence: 99%

“…However, such metallic alloys show some limitations, including low corrosion/wear resistance and unsuitable scratching and hardness properties. Therefore, to solve these drawbacks, several coatings have been proposed [57,101,105,108]. It was also concluded that zirconium-based coatings and OIH materials have been widely studied, as has the application, simultaneously, of polymers and zirconium enhanced several properties; namely, scratching, biocompatibility, bioactivity and hardness [53].…”

Section: Sol-gel Process: a Historical Perspective And Applicationsmentioning

confidence: 99%

See 1 more Smart Citation

Hybrid Sol–gel Coatings for Corrosion Mitigation: A Critical Review

Figueira

2020

Polymers

View full text Add to dashboard Cite

The corrosion process is a major source of metallic material degradation, particularly in aggressive environments, such as marine ones. Corrosion progression affects the service life of a given metallic structure, which may end in structural failure, leakage, product loss and environmental pollution linked to large financial costs. According to NACE, the annual cost of corrosion worldwide was estimated, in 2016, to be around 3%-4% of the world's gross domestic product. Therefore, the use of methodologies for corrosion mitigation are extremely important. The approaches used can be passive or active. A passive approach is preventive and may be achieved by emplacing a barrier layer, such as a coating that hinders the contact of the metallic substrate with the aggressive environment. An active approach is generally employed when the corrosion is set in. That seeks to reduce the corrosion rate when the protective barrier is already damaged and the aggressive species (i.e., corrosive agents) are in contact with the metallic substrate. In this case, this is more a remediation methodology than a preventive action, such as the use of coatings. The sol-gel synthesis process, over the past few decades, gained remarkable importance in diverse areas of application. Sol-gel allows the combination of inorganic and organic materials in a single-phase and has led to the development of organic-inorganic hybrid (OIH) coatings for several applications, including for corrosion mitigation. This manuscript succinctly reviews the fundamentals of sol-gel concepts and the parameters that influence the processing techniques. The state-of-the-art of the OIH sol-gel coatings reported in the last few years for corrosion protection, are also assessed. Lastly, a brief perspective on the limitations, standing challenges and future perspectives of the field are critically discussed.Polymers 2020, 12, 689 The development of OIH sol-gel coatings, based on siloxanes, for corrosion mitigation, has been widely studied in the last few years [2,31,[36][37][38]. Numerous studies have been conducted since the early 1990s [39,40]. The studies performed showed that siloxanes were effective in mitigating the corrosion processes of different metallic substrates. This development was mainly due to the need for alternative environmentally friend materials and processes to replace the traditional chromium-based pre-treatments. Hexavalent chromium (Cr (VI)) is carcinogenic and shows high environmental toxicity and its use has been forbidden since 2006. However, Cr(VI) based pre-treatments improve the coating adherence to the substrate and are effective corrosion inhibitors [41][42][43] which make its replacement challenging. The use of the sol-gel method to produce OIH coatings for corrosion mitigation suits the main requirements of what should be an environmentally friendly process (i.e., excludes washing stages; it is a waste-free method) and allows one to obtain coatings with high purity and specific pore volumes and surface areas. Since it is a mild synthesis...

show abstract

Section: Sol-gel Process: a Historical Perspective And Applicationsmentioning

confidence: 99%

Section: Sol-gel Process: a Historical Perspective And Applicationsmentioning

confidence: 99%

Hybrid Sol–gel Coatings for Corrosion Mitigation: A Critical Review

Figueira

2020

Polymers

View full text Add to dashboard Cite

show abstract

“…Further studies are required to test the bioactivity and biocompatibility of these promising biomedical materials in vitro and in vivo. Recently, published work [62] has shown that the TiO 2 /HAP (20 vol pct TiO 2 ) composite coatings exhibited well biocompatible properties, stem cells attached well onto the surface, proliferated, and presented a polygonal morphology different from the fibroblastic-like morphology found on 316L SS. Moreover, TiO 2 /HAP composite improved the corrosion resistance of the 316L SS implant and showed mechanical properties close to that of hard tissue once incubated in physiological conditions for 7 days, highlighting its potential application in hard tissue replacement.…”

Section: E Mechanical Propertiesmentioning

confidence: 99%

Hydroxyapatite-TiO2-SiO2-Coated 316L Stainless Steel for Biomedical Application

Sidane

Khireddine

Bir

et al. 2017

Metall Mater Trans A

View full text Add to dashboard Cite

This study investigated the effectiveness of titania (TiO 2) as a reinforcing phase in the hydroxyapatite (HAP) coating and silica (SiO 2) single layer as a bond coat between the TiO 2-reinforced hydroxyapatite (TiO 2 /HAP) top layer and 316L stainless steel (316L SS) substrate on the corrosion resistance and mechanical properties of the underlying 316L SS metallic implant. Single layer of SiO 2 film was first deposited on 316L SS substrate and studied separately. Water contact angle measurements, X-ray photoelectron spectroscopy, and Fourier transform infrared spectrophotometer analysis were used to evaluate the hydroxyl group reactivity at the SiO 2 outer surface. The microstructural and morphological results showed that the reinforcement of HAP coating with TiO 2 and SiO 2 reduced the crystallite size and the roughness surface. Indeed, the deposition of 50 vol pct TiO 2-reinforced hydroxyapatite layer enhanced the hardness and the elastic modulus of the HAP coating, and the introduction of SiO 2 inner layer on the surface of the 316L SS allowed the improvement of the bonding strength and the corrosion resistance as confirmed by scratch studies, nanoindentation, and cyclic voltammetry tests.

show abstract

“…10 The preparation of HA coating is one of the most important methods in surface modification techniques. Thus far, there have been many techniques to produce HA coating on implant surfaces, such as plasma spraying, 11 sol-gel techniques, 12 and electrophoretic deposition. 13 Unfortunately, these approaches usually require multiple steps, high temperature, special apparatus, and rigorous conditions that impede their application in the clinic.…”

Section: Introductionmentioning

confidence: 99%

Polydopamine-induced hydroxyapatite coating facilitates hydroxyapatite/polyamide 66 implant osteogenesis: an in vitro and in vivo evaluation

Xu¹,

Li²,

Wu³

et al. 2018

IJN

View full text Add to dashboard Cite

BackgroundHydroxyapatite/polyamide 66 (HA/P66) has been clinically used for several years owing to its good biocompatibility and bioactivity. However, it has been found that the osseointegration process of the HA/P66 implant takes a large amount of time because of the small amount of HA on its surface.MethodsTo increase the amount of HA and aid faster osseointegration, we prepared a HA coating using a biomimetic process assisted by polydopamine (PDA) on the HA/P66 substrate. The surface properties of the substrate modified by PDA and HA were characterized, and the capacity of biomaterials for osteogenic induction was investigated both in vitro and in vivo.ResultsThe HA coating was successfully prepared on the HA/P66 substrate and verified by X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and X-ray diffraction (XRD). The HA coating remained firmly attached to the underlying PDA-HA/P66 substrate even after strong ultrasound treatment for 1 h, and the calcium and phosphorus of the HA coating was continuously released in vitro in a slow manner. The formation of the HA coating on the PDA film greatly increased the hydrophilicity and surface roughness of HA/P66. In cell-based experiments, as compared with the HA/P66 substrate, the HA coating formation on the PDA film could facilitate the functions of C3H10T1/2 cells, including cell adhesion, proliferation, spreading, alkaline phosphatase activity, calcium nodule formation, and expression of osteogenic differentiation-related proteins. In addition, the HA/P66 scaffolds modified with PDA and HA coatings were implanted in rabbit femoral condyles. At 8 weeks after surgery, micro-computed tomography scanning (micro-CT) and hematoxylin–eosin (HE) staining revealed that more new bones were formed around the HA/P66 scaffold that was modified with a PDA-assisted HA coating.ConclusionThese results indicate that the preparation of a PDA-assisted HA coating by using a biomimetic process significantly improves the capacity of biomaterials for osteogenic induction.

show abstract

Biocompatibility of sol-gel hydroxyapatite-titania composite and bilayer coatings

Cited by 65 publications

References 52 publications

Hybrid Sol–gel Coatings for Corrosion Mitigation: A Critical Review

Hybrid Sol–gel Coatings for Corrosion Mitigation: A Critical Review

Hydroxyapatite-TiO2-SiO2-Coated 316L Stainless Steel for Biomedical Application

Polydopamine-induced hydroxyapatite coating facilitates hydroxyapatite/polyamide 66 implant osteogenesis: an in vitro and in vivo evaluation

Contact Info

Product

Resources

About