Biocompatibility of retrograde root filling materials: A review

Bodrumlu, Emre

doi:10.1111/j.1747-4477.2007.00085.x

Cited by 83 publications

(81 citation statements)

References 45 publications

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“…To be clinically feasible, further investigations are necessary to find the proper mixing ratio in order to improve the drawbacks of MTA without impairing the pre-existing advantages and to assess the biocompatibility. •황인남 1,5 •오원만 …”

Section: Discussionmentioning

confidence: 99%

Physical and chemical properties of experimental mixture of mineral trioxide aggregate and glass ionomer cement

Jeong

Yang

Park

et al. 2010

J Korean Acad Conserv Dent

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Objectives:The purpose of this study was to determine the setting time, compressive strength, solubility, and pH of mineral trioxide aggregate (MTA) mixed with glass ionomer cement (GIC) and to compare these properties with those of MTA, GIC, IRM, and SuperEBA. Materials and Methods: Setting time, compressive strength, and solubility were determined according to the ISO 9917 or 6876 method. The pH of the test materials was determined using a pH meter with specified electrode for solid specimen. Results: The setting time of MTA mixed with GIC was significantly shorter than that of MTA. Compressive strength of MTA mixed with GIC was significantly lower than that of other materials at all time points for 7 days. Solubility of 1 : 1 and 2 : 1 specimen from MTA mixed with GIC was significantly higher than that of other materials. Solubility of 1 : 2 specimen was similar to that of MTA. The pH of MTA mixed with GIC was 2-4 immediately after mixing and increased to 5-7 after 1 day. Conclusions: The setting time of MTA mixed with GIC was improved compared with MTA. However, other properties such as compressive strength and pH proved to be inferior to those of MTA. To be clinically feasible, further investigation is necessary to find the proper mixing ratio in order to improve the drawbacks of MTA without impairing the pre-existing advantages and to assess the biocompatibility. [J Kor Acad Cons Dent 2010;35(5):344-352.]

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Section: Discussionmentioning

confidence: 99%

Physical and chemical properties of experimental mixture of mineral trioxide aggregate and glass ionomer cement

Jeong

Yang

Park

et al. 2010

J Korean Acad Conserv Dent

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“…Low toxicity of MTA and GIC has been already well documented. 3,6,7,14,15 Research on the biocompatibility of GICs in conventional and surgical endodontics exhibit good biocompatibility for three main reasons: (i) they set with minimal exotherm; (ii) neutralization is generally sufficiently rapid that any potential irritation because of the presence of free acid is minimal; and (iii) the substances leached from the set cement are generally either benign or beneficial to the tissue in which the cement is placed. 15 Good biocompatibility of GIC is also presented in the result of this study.…”

Section: Basic Researchmentioning

confidence: 99%

“…2 MTA offers a biologically active substrate for bone cells and stimulates interlukin production because of its alkaline pH and calcium ion release. 3 The biocompatibility of MTA has been assessed in many studies. [3][4][5][6][7][8][9][10][11][12][13][14] Calcium hydroxide which is biocompatible with tissue, is the main compound released by MTA in water.…”

Section: Introductionmentioning

confidence: 99%

“…[3][4][5][6][7][8][9][10][11][12][13][14] Calcium hydroxide which is biocompatible with tissue, is the main compound released by MTA in water. 3 The results of an in vitro study showed that MTA was less toxic than amalgam, SuperEBA and IRM. 4 Kwon et al reported that MTA inhibits the stimulatory function of growth factors on granulation tissue formation and promotes the healing process modulated by bone-remodeling cells.…”

Section: Introductionmentioning

confidence: 99%

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Biocompatibility of experimental mixture of mineral trioxide aggregate and glass ionomer cement

Jeong

Bae

et al. 2010

J Korean Acad Conserv Dent

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Objectives:The purpose of the present in vitro study was to evaluate the biocompatibility of mineral trioxide aggregate (MTA) mixed with glass ionomer cement (GIC), and to compare it with that of MTA, GIC, IRM and SuperEBA. Materials and Methods: Experimental groups were divided into 3 groups such as 1 : 1, 2 : 1, and 1 : 2 groups depending on the mixing ratios of MTA powder and GIC powder. Instead of distilled water, GIC liquid was mixed with the powder. This study was carried out using MG-63 cells derived from human osteosarcoma. They were incubated for 1 day on the surfaces of disc samples and examined by scanning electron microscopy. To evaluate the cytotoxicity of test materials quantitatively, XTT assay was used. The cells were exposed to the extracts and incubated. Cell viability was recorded by measuring the optical density of each test well in reference to controls. Results: The SEM revealed that elongated, dense, and almost confluent cells were observed in the cultures of MTA mixed with GIC, MTA and GIC. On the contrary, cells on the surface of IRM or SuperEBA were round in shape. In XTT assay, cell viability of MTA mixed with GIC group was similar to that of MTA or GIC at all time points. IRM and SuperEBA showed significantly lower cell viability than other groups at all time points (p < 0.05).

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“…Mineral trioxide aggregate (ProRoot MTA, Dentsply Tulsa Dental Specialties, Tulsa, OK, USA) has shown promising results as a root-end filling material because of its sealing properties 11,12) , bioactivity 13) , and cementogenesis potential 14) . It has rapidly become the 'gold' standard for root-end filling materials 15) . However, poor handling characteristics, initial looseness, and slow setting time make MTA difficult to use 16) .…”

Section: Introductionmentioning

confidence: 99%

Effect of Er,Cr:YSGG laser irradiation on apical sealing ability of calcium silicatecontaining endodontic materials in root-end cavities

et al. 2014

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The aim of this research was to evaluate the apical sealing abilities of 60 root-end cavities filled with mineral trioxide aggregate (MTA) and iRoot BP cements after treated with either 17% EDTA solution or Er,Cr:YSGG laser irradiation. After the filling procedure, apical leakage quantity was measured at 4 weeks using a fluid filtration method. One root from each group was processed for scanning electron microscopy and energy dispersive X-ray spectroscopy analyses. Both EDTA/MTA and laser irradiation/MTA combinations showed significantly lower microleakage than EDTA/iRoot BP and laser irradiation/iRoot BP combinations (p<0.05). Between groups of the same filling material, there were no significant differences among specimens treated with EDTA or laser (p>0.05). Both MTA and iRoot-BP demonstrated tag-like structures within the dentinal tubules when used in conjunction with EDTA.

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Biocompatibility of retrograde root filling materials: A review

Cited by 83 publications

References 45 publications

Physical and chemical properties of experimental mixture of mineral trioxide aggregate and glass ionomer cement

Physical and chemical properties of experimental mixture of mineral trioxide aggregate and glass ionomer cement

Biocompatibility of experimental mixture of mineral trioxide aggregate and glass ionomer cement

Effect of Er,Cr:YSGG laser irradiation on apical sealing ability of calcium silicatecontaining endodontic materials in root-end cavities

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