Biochemistry of Peroxisomes

Evaluation of the role of the Endoplasmic Reticulum-Golgi transit in the biogenesis of peroxisomal membrane proteins in wild type and peroxisome biogenesis mutant CHO cells

“…They contain different enzymes, which participate in several metabolic pathways, particularly in lipid metabolism, such as the β-oxidation of fatty acids (mainly very long chain fatty acids) and synthesis of plasmalogens (Van den Bosch et al, 1992).…”

Dynamin-related Protein 1 (Drp1) Promotes Structural Intermediates of Membrane Division

“…The balance between these counteracting processes is essential for the maintenance of a functional mitochondrial structure and plays a role in mitochondrial biogenesis and metabolism, in mitophagy, and in neurodegenerative diseases (4 -6). On the other hand, peroxisomes are ubiquitous subcellular organelles that participate in a variety of important catabolic and anabolic functions, including hydrogen peroxide and lipid metabolism (7). It is thought that peroxisome proliferation also occurs by division, comprising three stages: elongation, constriction, and fission (8).…”

In-Depth Proteome Analysis of Arabidopsis Leaf Peroxisomes Combined with in Vivo Subcellular Targeting Verification Indicates Novel Metabolic and Regulatory Functions of Peroxisomes

“…The 19 peroxisomal proteins conclusively identified from this study potentially carry out novel metabolic and regulatory functions of peroxisomes. Thus, this study represents an important step toward defining the complete plant peroxisomal proteome.Surrounded by single membranes, peroxisomes are small, ubiquitous eukaryotic organelles mediating a wide range of oxidative metabolic activities that vary by the species, cell type, and environmental conditions in which the organism lives (Beevers, 1979;Van den Bosch et al, 1992). Plant peroxisomes are essential to physiological processes such as lipid metabolism, photorespiration, and plant hormone biosynthesis and metabolism (Olsen and Harada,…”

“…Surrounded by single membranes, peroxisomes are small, ubiquitous eukaryotic organelles mediating a wide range of oxidative metabolic activities that vary by the species, cell type, and environmental conditions in which the organism lives (Beevers, 1979;Van den Bosch et al, 1992). Plant peroxisomes are essential to physiological processes such as lipid metabolism, photorespiration, and plant hormone biosynthesis and metabolism (Olsen and Harada, 1995;Zolman et al, 2000;Hayashi and Nishimura, 2003;Nyathi and Baker, 2006;Reumann and Weber, 2006).…”