2011
DOI: 10.1016/b978-0-12-385855-9.00004-7
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Biochemistry of Hellp Syndrome

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Cited by 32 publications
(21 citation statements)
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“…To the best of our knowledge, this is the first study evaluating the values of serum Angs-1 and -2 for the diagnosis of HELLP syndrome in PE patients. Better understanding in the pathophysiology of HELLP syndrome may improve the differential diagnosis and clinical management; it probably represents a severe form of PE with greater hepatic inflammation and greater activation of the coagulation system, but the relationship between the two diseases remains controversial [24,25]. The prognostic performance of the contemporary workup that is routinely used is not acceptable for the differential diagnosis of PE and HELLP syndrome.…”
Section: Discussionmentioning
confidence: 97%
“…To the best of our knowledge, this is the first study evaluating the values of serum Angs-1 and -2 for the diagnosis of HELLP syndrome in PE patients. Better understanding in the pathophysiology of HELLP syndrome may improve the differential diagnosis and clinical management; it probably represents a severe form of PE with greater hepatic inflammation and greater activation of the coagulation system, but the relationship between the two diseases remains controversial [24,25]. The prognostic performance of the contemporary workup that is routinely used is not acceptable for the differential diagnosis of PE and HELLP syndrome.…”
Section: Discussionmentioning
confidence: 97%
“…This is the same percentage as in the general population, were percentages between the 7.0 and 10.0% are reported (Vigil-De Gracia 2001). One pregnancy (2.0%) ended in eclampsia; this is slightly higher than the general population, where percentages range between 0.2 and 0.6% (Benedetto et al 2011). However, this was just one child.…”
Section: Discussionmentioning
confidence: 93%
“…Mothers with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome were also excluded because it is associated with hemolysis, thus increasing CO levels. In addition, some investigators consider HELLP syndrome a separate entity from PE [14,53] .…”
Section: Methodsmentioning
confidence: 97%