Biochemical Synthesis in Microstructured Silicon Wafer

Abstract

In biotechnics microsystems have been introduced primarily for analytical purpose in the past few years. Recently miniaturised microtiterplates, so called nanotiterplates, as efficient tools in screening have been discussed.In a case study we demonstrate the application of cell-free translation or transcription/translation and nucleic acid amplification in such nanotiterplates.The results show the potential range of applications of nanotiterplates for biotechnology even for biochemical systems, which have not been discussed as miniaturisable in screening.