Biochemical Profile of Chronic Kidney Disease (CKD) Patients in Various Age and Gender Group Subjects Visiting Kist Medical College &amp; Teaching Hospital, Kathmandu

Paudel, YP; Dahal, S; Acharya, Tushar; Joshi, Asim; Shrestha, Basudha; Khanal, Madhav; Kafle, Deepak

doi:10.3126/jcmc.v3i2.8441

Cited by 4 publications

(8 citation statements)

References 14 publications

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“…5 Similar etiological proportions have been reported by various studies in different tertiary centres of Nepal. 6 , 7 In contrast to ours, studies from India report diabetes as the most common underlying comorbidity followed by hypertension. 10 , 11 …”

Section: Discussioncontrasting

confidence: 93%

“…4 Various institutional studies of Nepal have shown hypertension and diabetes as the major causes of CKD with a prevalence of 24.5% and 5.8% respectively. [5][6][7][8] The more widespread efforts at prevention, early detection, evaluation, and management of CKD and antecedent conditions could prevent complications of decreased kidney function.…”

Section: Introductionmentioning

confidence: 99%

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End Stage Renal Disease among Patients Undergoing Haemodialysis at a Tertiary Care Centre: A Descriptive Cross-sectional Study

et al. 2022

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Introduction: Chronic kidney disease is defined as structural or functional damage of the kidney persisting for three or more months. Studies have shown hypertension and diabetes as the leading causes of chronic kidney disease. The aim of this study is to find out the prevalence of end-stage renal disease patients undergoing haemodialysis in a tertiary care hospital. Methods: This was a descriptive cross-sectional study conducted among 96 patients undergoing haemodialysis from February 13, 2021 to April 4, 2021 in the hemodialysis unit of a tertiary care centre after receiving ethical clearance from the Institutional Review Committee (Reference number: 354). Convenience sampling was done and all patients older than 18 years who were on maintenance haemodialysis on an outpatient basis were included in the study. Data were collected using a self-administered questionnaire. Data were analysed using the Statistical Package for the Social Science version 22.0. Point estimate at 95% Confidence Interval was calculated along with frequency and percentages for binary data and mean with standard deviation for continuous data. Results: Among 96 patients undergoing haemodialysis, the prevalence of end-stage renal disease was 83 (86.45%) (79.60-93.30 at 95% Confidence Interval). The most common underlying condition was hypertensive nephropathy in 34 (40.96%) patients, followed by both hypertensive and diabetic nephropathy in 26 (31.33%) patients. Conclusions: The prevalence of end-stage renal disease in our study was higher when compared to similar studies conducted in similar settings. Early diagnosis and adequate treatment of hypertension and diabetes could be crucial to reducing the prevalence of the end-stage renal disease.

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Section: Discussioncontrasting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

End Stage Renal Disease among Patients Undergoing Haemodialysis at a Tertiary Care Centre: A Descriptive Cross-sectional Study

et al. 2022

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“…The present study was conducted in order to identify biochemical changes and prolactin secretion in CKD patients in comparison with controls, with emphasis on differences which may have had an impact on diagnostic or therapeutic approaches. Several studies correspond that chronic kidney disease typically increases with age 8,12 which supports this study. Older adults are, therefore, at increased risk for chronic kidney disease.…”

Section: Discussionsupporting

confidence: 90%

“…CKD can be detected via simple biochemical tests. 8 These tests include a creatinine-based estimate of the glomerular filtration rate (GFR), serum creatinine 2 , RBC, urea etc. 9 CKD is characterized by elevation of serum prolactin levels.…”

Section: Introductionmentioning

confidence: 99%

Studies on Biochemical Changes and Prolactin Level Evaluation in Patients with Chronic Kidney Disease

Rahman¹,

Kabir²,

S³

2019

KYAMC j.

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Background: Chronic kidney disease (CKD) is progressive loss in kidney function over a period of months or years. CKD is an internationally recognized public health problem affecting 5-10% of the world population and day-by-day the number of cases are increasing at an alarming rate. This study was conducted in Khwaja Yunus Ali Medical College Hospital in Enayetpur, Sirajganj. Objectives: To assess serum creatinine, hemoglobin (Hb), urea, red blood cell (RBC), protein creatinine ratio (PCR) and prolactin in CKD patients. Material and Methods: This study included 110 patients, 61 were males and 49 were females and their age range 1 to more than 60 years.The control group also consisted of same number of participants as the patients, who were free from signs and symptoms of kidney disease and prolactin hormone disorders. Results: The study shows that all the biochemical parameters in CKD patients were found to be significantly high compared with control group (P<0.001). Serum prolactin concentrations in CKD patients were also increased significantly compared with control group (P<0.05). It was found that male CKD patients secret more prolactin hormone than male control. Conclusion: Although males are more prone to chronic kidney disease, but the percentage of females is not negligible. All the biochemical parameters and prolactin level changed significantly in the CKD patients. It is interesting that in case of CKD, male's prolactin secretion becomes higher.

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“…Regarding comorbidity, the majority had hypertension followed by diabetes mellitus which is relevant with previous findings. 23,24 This is common for patients having vascular problems.…”

Section: Discussion Participants' Sociodemographic Characteristicsmentioning

confidence: 99%

Knowledge, Self-Efficacy, Self-Management Behavior of the Patients With Predialysis Chronic Kidney Disease

Moktan¹,

Leelacharas²,

Prapaipanich³

2019

Rama Med J

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Background: Chronic kidney disease (CKD) is an emerging global public health problem. Control of risk factors and prevention of complications can delay the progression to end-stage renal disease. Self-efficacy and self-management behavior in patients with predialysis CKD has not been investigated in Nepal. Objectives: To describe knowledge of CKD, self-efficacy, and self-management behavior in patients with predialysis CKD and to determine the relationships between knowledge in CKD and self-efficacy with self-management behavior. Methods: Ninety-seven predialysis CKD patients visiting nephrology clinic of a tertiary care hospital in Kathmandu, Nepal were recruited from November 2016 to December 2016. Questionnaires comprised of sociodemographic data, CKD knowledge, self-efficacy, and self-management behavior questionnaires were used. Data were analyzed, using descriptive statistics and Pearson product moment correlation coefficient. Results: The mean age of 97 participants was 45.67 years. There were 3 stages of CKD among participants: stage G4 (54.64%), stage G3 (42.27%), and stage G2 (3.09%), respectively. Hypertension was the most common comorbidity (81.44%) followed by diabetes mellitus (30.92%). Predialysis CKD patients had a moderate level of knowledge on CKD and self-efficacy and high level of self-management behavior. There were positive relationships between knowledge in CKD and self-management behavior (r = 0.52; P < .05), and between self-efficacy and self-management behavior (r = 0.39; P < .05). Conclusions: This study suggested that education, counseling, workshop to increase the knowledge, self-efficacy, and self-management behavior might be helpful for the predialysis CKD patients. Healthcare providers can educate, motivate, and train the patients to practice self-management behavior to delay the progression of CKD.

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Biochemical Profile of Chronic Kidney Disease (CKD) Patients in Various Age and Gender Group Subjects Visiting Kist Medical College & Teaching Hospital, Kathmandu

Cited by 4 publications

References 14 publications

End Stage Renal Disease among Patients Undergoing Haemodialysis at a Tertiary Care Centre: A Descriptive Cross-sectional Study

End Stage Renal Disease among Patients Undergoing Haemodialysis at a Tertiary Care Centre: A Descriptive Cross-sectional Study

Studies on Biochemical Changes and Prolactin Level Evaluation in Patients with Chronic Kidney Disease

Knowledge, Self-Efficacy, Self-Management Behavior of the Patients With Predialysis Chronic Kidney Disease

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