Biochemical Mechanisms of Acetaminophen (Paracetamol) Induced Hepatic and Renal Toxicity

Drug Nephrotoxicity

“…This concentra tion gradient correlates with the extent of protein covalent binding of AP AP within the kidney (70). This concentra tion gradient correlates with the extent of protein covalent binding of AP AP within the kidney (70).…”

“…The enzyme distribution appears to be central to the develop ment of acute and chronic nephrotoxicity (70). The enzyme distribution appears to be central to the develop ment of acute and chronic nephrotoxicity (70).…”