Biochemical composition of Phleum pratense pollen grains: A review

Visez, Nicolas; Nadaï, Patricia de; Choël, M.; Farah, Jinane; Hamzé, Mona; Sénéchal, Hélène; Pauwels, Maxime; Frérot, Hélène; Thibaudon, M.; Poncet, Pascal

doi:10.1016/j.molimm.2021.05.014

Cited by 15 publications

(11 citation statements)

References 126 publications

(198 reference statements)

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“…Circumstantial evidence for such a relationship can be found in the observation that food allergens such as Pen a 1 (shrimp), and Ara h 1 and Ara h 2 (peanut) comprise a significant portion (up to 20%) of the total protein that humans consume when eating shrimp and peanuts (12)(13)(14). Similar results have been reported for both indoor and outdoor aeroallergen sources such as cockroach frass (Bla g 1, 18% total protein), Timothy grass pollen (Phl p 5, 6.4% total protein), and house dust mite extracts (Der p 1, ∼33% total protein) (15)(16)(17). Epidemiological studies provide further evidence for an empirical link between abundance and allergenicity.…”

Section: Abundance and Stability As Important Characteristics Of Allergenssupporting

confidence: 63%

Abundance and Stability as Common Properties of Allergens

Foo¹,

Mueller²

2021

Front. Allergy

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There have been many attempts to identify common biophysical properties which differentiate allergens from their non-immunogenic counterparts. This review will focus on recent studies which examine two such factors: abundance and stability. Anecdotal accounts have speculated that the elevated abundance of potential allergens would increase the likelihood of human exposure and thus the probability of sensitization. Similarly, the stability of potential allergens dictates its ability to remain a viable immunogen during the transfer from the source to humans. This stability could also increase the resilience of potential allergens to both gastric and endosomal degradation, further skewing the immune system toward allergy. Statistical analyses confirm both abundance and stability as common properties of allergens, while epidemiological surveys show a correlation between exposure levels (abundance) and allergic disease. Additional studies show that changes in protein stability can predictably alter gastric/endosomal processing and immunogenicity, providing a mechanistic link between stability and allergenicity. However, notable exceptions exist to both hypotheses which highlight the multifaceted nature of immunological sensitization, and further inform our understanding of some of these other factors and their contribution to allergic disease.

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Section: Abundance and Stability As Important Characteristics Of Allergenssupporting

confidence: 63%

Abundance and Stability as Common Properties of Allergens

Foo¹,

Mueller²

2021

Front. Allergy

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“…Allergies caused by pollen are widespread in the world population [ 28 ], and for a long time, it was thought that the main causative agent of pollen-associated allergies was the protein content of the grains. We now know that other biomolecules carried by pollen grains can be responsible for the activation of the immune response, including molecules naturally associated with pollen, such as lipids, protease, and NADPH oxidase, or pollutants of gaseous or particulate nature that adsorb to the grains [ 29 ]. Harsh washing conditions, using organic solvents, strong alkali, and strong acids can be employed to eliminate allergens without affecting the main structure of the pollen grain.…”

Section: Discussionmentioning

confidence: 99%

Sporopollenin Capsules as Biomimetic Templates for the Synthesis of Hydroxyapatite and β-TCP

De Mori,

Quizon,

Dalton

et al. 2024

Biomimetics

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Pollen grains, with their resilient sporopollenin exine and defined morphologies, have been explored as bio-templates for the synthesis of calcium phosphate minerals, particularly hydroxyapatite (HAp) and β-tricalcium phosphate (TCP). Various pollen morphologies from different plant species (black alder, dandelion, lamb’s quarters, ragweed, and stargazer lily) were evaluated. Pollen grains underwent acid washing to remove allergenic material and facilitate subsequent calcification. Ragweed and lamb’s quarter pollen grains were chosen as templates for calcium phosphate salts deposition due to their distinct morphologies. The calcification process yielded well-defined spherical hollow particles. The washing step, intended to reduce the protein content, did not significantly affect the final product; thus, justifying the removal of this low-yield step from the synthesis process. Characterisation techniques, including X-ray diffraction, scanning electron microscopy, Fourier-transform infrared spectroscopy, and thermal gravimetric analysis, confirmed the successful calcification of pollen-derived materials, revealing that calcified grains were principally composed of calcium deficient HAp. After calcination, biphasic calcium phosphate composed of HAp and TPC was obtained. This study demonstrated the feasibility of using pollen grains as green and sustainable bio-templates for synthesizing biomaterials with controlled morphology, showcasing their potential in biomedical applications such as drug delivery and bone regeneration.

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“…187 In the atmosphere, pollen can also release subparticles (0.5−3.0 μm in size) 182 in a process that is triggered by water and/or high relative humidity and is common during thunderstorms. 182,183,185 These subparticles are pre-existing bodies that can be found on the external surface (named "Ubisch bodies") 176 and/or inside (e.g., starch granules) 186,188 intact pollen grains, depending on the species. Atmospheric pollutants can also interact with pollen in a variety of ways (reviewed by Seńećhal et al 185 ).…”

Section: Pollenmentioning

confidence: 99%

“…For example, a study on corn pollen retention on milkweed leaves showed that a single rain event can remove 54–86% of deposited grains . Third, when wetted, pollen releases water-soluble compounds including, among others, sugars (e.g., fructose, used also as a chemical tracer for pollen , ), polyunsaturated fatty acids, and proteins. ,− Some of these substances have allergenic properties, whereas others can nucleate ice crystals . In the atmosphere, pollen can also release subparticles (0.5–3.0 μm in size) in a process that is triggered by water and/or high relative humidity and is common during thunderstorms. ,, These subparticles are pre-existing bodies that can be found on the external surface (named “Ubisch bodies”) and/or inside (e.g., starch granules) , intact pollen grains, depending on the species.…”

Section: Chemicals From the Environmentmentioning

confidence: 99%

The Chemical Landscape of Leaf Surfaces and Its Interaction with the Atmosphere

Ossola,

Farmer

2024

Chem. Rev.

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Atmospheric chemists have historically treated leaves as inert surfaces that merely emit volatile hydrocarbons. However, a growing body of evidence suggests that leaves are ubiquitous substrates for multiphase reactions−implying the presence of chemicals on their surfaces. This Review provides an overview of the chemistry and reactivity of the leaf surface's "chemical landscape", the dynamic ensemble of compounds covering plant leaves. We classified chemicals as endogenous (originating from the plant and its biome) or exogenous (delivered from the environment), highlighting the biological, geographical, and meteorological factors driving their contributions. Based on available data, we predicted ≫2 μg cm −2 of organics on a typical leaf, leading to a global estimate of ≫3 Tg for multiphase reactions. Our work also highlighted three major knowledge gaps: (i) the overlooked role of ambient water in enabling the leaching of endogenous substances and mediating aqueous chemistry; (ii) the importance of phyllosphere biofilms in shaping leaf surface chemistry and reactivity; (iii) the paucity of studies on the multiphase reactivity of atmospheric oxidants with leaf-adsorbed chemicals. Although biased toward available data, we hope this Review will spark a renewed interest in the leaf surface's chemical landscape and encourage multidisciplinary collaborations to move the field forward. CONTENTS

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Biochemical composition of Phleum pratense pollen grains: A review

Cited by 15 publications

References 126 publications

Abundance and Stability as Common Properties of Allergens

Abundance and Stability as Common Properties of Allergens

Sporopollenin Capsules as Biomimetic Templates for the Synthesis of Hydroxyapatite and β-TCP

The Chemical Landscape of Leaf Surfaces and Its Interaction with the Atmosphere

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