Abstract:Aims: Ebosin, a novel exopolysaccharide (EPS) produced by Streptomyces sp. 139 has antagonistic activity for interleukin‐1 receptor (IL‐1R) in vitro and remarkable anti‐rheumatic arthritis activity in vivo. Ebosin biosynthesis gene (ste) cluster has been identified in our laboratory. This paper reports our effort to characterize the function of ste11 gene.
Methods and Results: After the ste11 gene was cloned and expressed in Escherichia coli BL21, the recombinant Ste11 was purified and found capable of catal… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.