Biochemical Basis of the Antimicrobial Activity of Quinazolinone Derivatives in the Light of Insights Into the Features of the Chemical Structure and Ways of Binding to Target Molecules. A Review
M. A. Samotruyeva,
A. A. Starikova,
O. A. Bashkina
et al.
Abstract:The review characterizes the role of the main targets of antibacterial agents: “efflux pumps”; enzymes (DNA-hyruases as a subclass of topoisomerases, homoserine transacetylase, various classes of sorbitases, aromatics, lipoteichoyl synthase, polyketide synthase, pantothenate synthetase, acetyl-CoA carboxylase, sensory histidine kinase, kinase, cyclooxygenase, etc.); penicillin-binding protein; quorum signaling and adhesin systems in important biochemical processes of pathogen maintenance and virulence manifest… Show more
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