Biochemical and Physiological Clues to the Nature of Psoriasis

Shelley, Walter B.

doi:10.1001/archderm.1958.01560070016003

Cited by 53 publications

(20 citation statements)

References 57 publications

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“…Former studies concur that the Koebner response should be expected to occur only when the disease is in an eruptive state 49 . More recent investigations suggest that rupture of the epidermis can initiate the Koebner response, but secondary dermal events are necessary for a psoriatic lesion to form 50 .…”

Section: Koebner Response Revisitedmentioning

confidence: 98%

Tattoo-Associated Dermatoses: A Case Report and Review of the Literature

Jacob

2002

Dermatol Surg

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Section: Koebner Response Revisitedmentioning

confidence: 98%

Tattoo-Associated Dermatoses: A Case Report and Review of the Literature

Jacob

2002

Dermatol Surg

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“…Significant improvement in PASI was also seen before and after treatment. Biochemical changes are important not only in understanding the pathogenesis of psoriasis but also act as a diagnostic and prognostic parameter in psoriasis in acute exacerbation [19]. In addition, the recognition of triggering factors in psoriasis not only helps in the prevention of disease exacerbation but also its better management.…”

Section: Conclussionmentioning

confidence: 99%

Estimation of peroxisome proliferators – activated receptor γ gene expression in inflammatory skin diseases: atopic dermatitis and psoriasis

Mahgoub¹,

Tawdy²,

Metwally³

et al. 2014

Our Dermatol Online

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Introduction: Psoriasis is a genetically determined chronic disease of skin in which a number of biochemical alterations take place during its course. The main objectives of our study were to calculate various biochemical parameters in psoriasis correlate them clinically. Materials and Methods: An attempt was made to detect the biochemical changes during its exacerbations. Fifty biopsy proved psoriasis patients were selected. Clinical examination and the various biochemical tests were performed at the time of enrollment and at the end of eight weeks of treatment. Results: Hyperurecemia was seen in 16% patients and hypocalcemia was seen in 10 % patients and hypoalbuminaemia was seen in 56% patients. Conclusion: With improvement of clinical picture, a shift of biochemical values towards normal was recorded.

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“…The time period from injury to psoriasis is diverse; even with the same patient [11] . In general, the interval to koebnerization is between 10 and 20 days, but may be as short as 3 days or as long as 2 years [12] . This lag period refl ects the degree of sensitivity for development of the Koebner response, which may be a unique characteristic of the patient's skin [13] .…”

Section: Trauma and Psoriasismentioning

confidence: 99%

Exogenous Factors and Psoriasis

Dika

Maibach

2004

Exog Dermatol

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Psoriasis is a chronic relapsing disease characterized by variable clinical features. Several factors may exacerbate its manifestations, or even trigger the disease, such as traumatic injury to the skin, physical and psychological stress, cold weather, excessive alcohol intake, and drugs such as lithium and beta-blockers. We describe the most common features of psoriasis and the exogenous factors that may induce, trigger or exacerbate the disease.

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Biochemical and Physiological Clues to the Nature of Psoriasis

Cited by 53 publications

References 57 publications

Tattoo-Associated Dermatoses: A Case Report and Review of the Literature

Tattoo-Associated Dermatoses: A Case Report and Review of the Literature

Estimation of peroxisome proliferators – activated receptor γ gene expression in inflammatory skin diseases: atopic dermatitis and psoriasis

Exogenous Factors and Psoriasis

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