1958
DOI: 10.1001/archderm.1958.01560070016003
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Biochemical and Physiological Clues to the Nature of Psoriasis

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Cited by 53 publications
(20 citation statements)
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“…Former studies concur that the Koebner response should be expected to occur only when the disease is in an eruptive state 49 . More recent investigations suggest that rupture of the epidermis can initiate the Koebner response, but secondary dermal events are necessary for a psoriatic lesion to form 50 .…”
Section: Koebner Response Revisitedmentioning
confidence: 98%
“…Former studies concur that the Koebner response should be expected to occur only when the disease is in an eruptive state 49 . More recent investigations suggest that rupture of the epidermis can initiate the Koebner response, but secondary dermal events are necessary for a psoriatic lesion to form 50 .…”
Section: Koebner Response Revisitedmentioning
confidence: 98%
“…Significant improvement in PASI was also seen before and after treatment. Biochemical changes are important not only in understanding the pathogenesis of psoriasis but also act as a diagnostic and prognostic parameter in psoriasis in acute exacerbation [19]. In addition, the recognition of triggering factors in psoriasis not only helps in the prevention of disease exacerbation but also its better management.…”
Section: Conclussionmentioning
confidence: 99%
“…The time period from injury to psoriasis is diverse; even with the same patient [11] . In general, the interval to koebnerization is between 10 and 20 days, but may be as short as 3 days or as long as 2 years [12] . This lag period refl ects the degree of sensitivity for development of the Koebner response, which may be a unique characteristic of the patient's skin [13] .…”
Section: Trauma and Psoriasismentioning
confidence: 99%